VSIG8抗体,Rabbit Polyclonal VSIG8 Antibody
  • VSIG8抗体,Rabbit Polyclonal VSIG8 Antibody
  • VSIG8抗体,Rabbit Polyclonal VSIG8 Antibody
  • VSIG8抗体,Rabbit Polyclonal VSIG8 Antibody

VSIG8抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
QQ交谈 微信洽谈

产品详情

中文名称:VSIG8抗体英文名称:Rabbit Polyclonal VSIG8 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2124 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: VSIG8
2025-05-11 VSIG8抗体 Rabbit Polyclonal VSIG8 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2124 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200-1/400 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

WB Predicted band size44 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human VSIG8
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse heart tissue and KB cell lysates, Primary antibody: P02002(VSIG8 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P02002(VSIG8 Antibody) at dilution 1/240. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P02002(VSIG8 Antibody) at dilution 1/240. (Original magnification: ×200)    


           

参考文献

以下是关于VSIG8抗体的示例参考文献(注:以下内容为模拟示例,实际文献需通过学术数据库查询):

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1. **文献名称**: *VSIG8 as a Novel Immune Checkpoint Molecule: Characterization of Its Inhibitory Role in T Cell Activation*

**作者**: Liu, X. et al.

**摘要**: 本研究利用抗VSIG8抗体阻断VSIG8与配体的相互作用,发现其可显著增强T细胞的活化和细胞因子分泌,提示VSIG8可能作为免疫检查点分子,在肿瘤免疫逃逸中发挥作用。

2. **文献名称**: *Development of a Monoclonal Antibody Against VSIG8 for Tumor Microenvironment Analysis*

**作者**: Chen, H. & Wang, Y.

**摘要**: 文章报道了一种高特异性抗VSIG8单克隆抗体的开发,并通过免疫组化证实VSIG8在多种肿瘤基质细胞中高表达,其表达水平与患者预后呈负相关。

3. **文献名称**: *Targeting VSIG8 with Therapeutic Antibodies Attenuates Colitis in Murine Models*

**作者**: Park, S. et al.

**摘要**: 通过抗VSIG8抗体的体内实验,研究发现其可减轻小鼠结肠炎模型的炎症反应,表明靶向VSIG8可能为自身免疫性疾病提供新治疗策略。

4. **文献名称**: *VSIG8 in Immune Regulation: A Review of Antibody-Based Functional Studies*

**作者**: Zhang, L. & Gupta, R.

**摘要**: 综述总结了VSIG8在免疫调控中的功能机制,重点讨论了抗体干预实验揭示的其在调节巨噬细胞极化和Treg细胞功能中的作用。

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**建议**:如需真实文献,请通过PubMed、Web of Science或Google Scholar检索关键词“VSIG8 antibody”或“VSIG8 immune function”,并筛选近5年研究以获取最新进展。

       

背景信息

The V-set and immunoglobulin domain-containing protein 8 (VSIG8) is a transmembrane protein belonging to the immunoglobulin superfamily (IgSF). It is primarily expressed in specific tissues, including the testis and certain immune cells. VSIG8 has garnered interest due to its structural features, such as extracellular V-set and Ig-like domains, which suggest roles in cell-cell interactions and immune regulation. Although its precise biological functions remain under investigation, VSIG8 is hypothesized to participate in immune modulation, potentially influencing T-cell activity or serving as a checkpoint molecule in immune responses.

VSIG8 antibodies are tools developed to detect, quantify, or inhibit VSIG8 in experimental settings. These antibodies enable researchers to study VSIG8's expression patterns, localization, and interactions in healthy and diseased tissues. Recent studies highlight its potential relevance in cancer immunology, where VSIG8 may contribute to tumor immune evasion, akin to other checkpoint proteins like PD-1/PD-L1. Antibodies targeting VSIG8 could thus have therapeutic applications, such as enhancing anti-tumor immunity.

Despite progress, the functional mechanisms of VSIG8 remain partially unresolved. Current research focuses on elucidating its ligands, signaling pathways, and tissue-specific roles. VSIG8 antibodies are critical reagents in these efforts, supporting both basic research and translational studies aimed at exploring VSIG8 as a biomarker or therapeutic target in immune-related disorders.

       
关键字: VSIG8抗体;VSIG8;VSIG8 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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