RNF148抗体,Rabbit Polyclonal RNF148 Antibody
  • RNF148抗体,Rabbit Polyclonal RNF148 Antibody
  • RNF148抗体,Rabbit Polyclonal RNF148 Antibody

RNF148抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-12
QQ交谈 微信洽谈

产品详情

中文名称:RNF148抗体英文名称:Rabbit Polyclonal RNF148 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2774 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: RNF148
2025-05-12 RNF148抗体 Rabbit Polyclonal RNF148 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2774 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesAFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human FGF1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10719(FGF1 Antibody) at dilution 1/25. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P10719(FGF1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是几篇关于RNF148抗体的虚构参考文献示例(仅供格式参考,实际文献需通过学术数据库查询):

---

1. **文献名称**: *RNF148 mediates p53 ubiquitination in colorectal cancer cells*

**作者**: Li, X., Zhang, Y., & Wang, H.

**摘要**: 本研究利用RNF148特异性抗体,发现RNF148通过泛素化修饰p53蛋白调控结直肠癌细胞凋亡,提示其可能作为癌症治疗的潜在靶点。

2. **文献名称**: *Development of a novel monoclonal antibody for RNF148 and its application in hepatocellular carcinoma*

**作者**: Tanaka, K., et al.

**摘要**: 报道了一种高特异性RNF148单克隆抗体的开发,并证实其在肝细胞癌组织中高表达,与患者预后不良相关。

3. **文献名称**: *RNF148 interacts with β-catenin in Wnt signaling pathway*

**作者**: Gupta, S., & Lee, J.

**摘要**: 通过免疫共沉淀(Co-IP)结合RNF148抗体,揭示了RNF148与β-catenin的相互作用,调控Wnt信号通路及胚胎发育过程。

4. **文献名称**: *RNF148 knockout mice exhibit defective DNA damage repair*

**作者**: Müller, R., et al.

**摘要**: 利用RNF148抗体进行蛋白表达分析,发现RNF148缺失导致小鼠细胞DNA损伤修复能力下降,证实其在基因组稳定性中的作用。

---

建议通过 **PubMed、Web of Science** 或 **Google Scholar** 查询真实文献,关键词如“RNF148 antibody”、“RNF148 ubiquitin”或“RNF148 function”。

       

背景信息

The RNF148 antibody is a research tool designed to target the RING finger protein 148 (RNF148), a member of the RING finger family characterized by a conserved zinc-binding domain critical for E3 ubiquitin ligase activity. RNF148 is implicated in ubiquitination, a post-translational modification process regulating protein degradation, localization, and interactions. While its biological functions remain less characterized compared to other RING family proteins, studies suggest RNF148 may play roles in cellular processes such as cell cycle regulation, DNA repair, or apoptosis, potentially interacting with substrates involved in these pathways. Dysregulation of ubiquitination enzymes like RNF148 is often linked to cancer, neurodegenerative disorders, or immune diseases, making it a subject of interest in disease mechanism research.

RNF148 antibodies are typically developed using recombinant protein fragments or synthetic peptides to ensure specificity. They enable detection and analysis of RNF148 expression levels, subcellular localization (e.g., nucleus, cytoplasm), and interaction partners via techniques like Western blotting, immunofluorescence, or immunoprecipitation. Validated antibodies help explore RNF148's tissue distribution, overexpression/knockdown effects, and its role in ubiquitin-proteasome pathways. However, limited commercial availability and functional data necessitate careful validation for cross-reactivity and batch consistency. Ongoing research aims to clarify RNF148's physiological and pathological relevance, positioning this antibody as a key reagent for dissecting its contributions to cellular homeostasis and disease.

       


关键字: RNF148抗体;RNF148;RNF148 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

RNF148抗体相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
询价
上海华盈生物医药科技有限公司
2025-12-28
¥1180
VIP1年
上海抚生实业有限公司
2025-12-31
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.