KLF11抗体,Rabbit Polyclonal KLF11 Antibody
  • KLF11抗体,Rabbit Polyclonal KLF11 Antibody
  • KLF11抗体,Rabbit Polyclonal KLF11 Antibody
  • KLF11抗体,Rabbit Polyclonal KLF11 Antibody

KLF11抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:KLF11抗体英文名称:Rabbit Polyclonal KLF11 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3524 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: KLF11
2025-05-13 KLF11抗体 Rabbit Polyclonal KLF11 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3524 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesFKLF; FKLF1; MODY7; TIEG2; Tieg3
WB Predicted band size55 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human KLF11
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: HUVEC cells, NIH/3T3 cells, Hela cells, 293T cells, Primary antibody: P07405(KLF11 Antibody) at dilution 1/475, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


           

参考文献

以下是关于KLF11抗体的3篇文献示例(内容为虚构,仅供格式参考):

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1. **文献名称**: *"KLF11 Antibody Validation in Pancreatic Cancer Models"*

**作者**: Smith A, et al.

**摘要**: 研究利用KLF11特异性抗体分析胰腺癌细胞中KLF11的蛋白表达水平,发现其与肿瘤抑制基因的转录调控相关,并证实该抗体在免疫组化(IHC)和Western blot中的高特异性。

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2. **文献名称**: *"Role of KLF11 in Diabetic Nephropathy: An Antibody-Based Study"*

**作者**: Zhang L, et al.

**摘要**: 通过KLF11抗体检测糖尿病肾病患者肾组织样本,揭示KLF11在炎症和纤维化通路中的调控作用,提示其作为潜在治疗靶点的价值。

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3. **文献名称**: *"KLF11 Antibody Application in Neuronal Differentiation Assays"*

**作者**: Brown C, et al.

**摘要**: 研究使用KLF11抗体探究神经干细胞分化过程中KLF11的动态表达,证实其通过结合特定启动子区域调控神经元成熟相关基因。

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如需真实文献,建议通过PubMed或Google Scholar以“KLF11 antibody” + “应用领域(如cancer/diabetes)”为关键词检索。

       

背景信息

The Krüppel-like factor 11 (KLF11) antibody is a research tool designed to detect and study the KLF11 protein, a member of the Krüppel-like family of zinc finger transcription factors. KLF11. also known as TIEG2. regulates gene expression by binding to GC-rich DNA sequences and recruiting co-repressor complexes like Sin3/HDAC to modulate chromatin structure. It plays roles in cellular processes such as proliferation, differentiation, and apoptosis, with implications in metabolic homeostasis, cancer, fibrosis, and neurodegenerative diseases.

KLF11 antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to analyze protein expression, localization, and interactions in tissues or cell lines. Researchers employ these antibodies to explore KLF11's involvement in pathologies; for instance, its downregulation in pancreatic cancer or its regulatory effects on insulin sensitivity in diabetes.

Antibodies targeting KLF11 are typically raised in rabbits or mice, with options for monoclonal or polyclonal formats. Validation includes specificity checks using knockout controls or siRNA-mediated silencing. Commercial KLF11 antibodies often cite applications in studying TGF-β signaling, oxidative stress responses, or epigenetic mechanisms. However, performance may vary depending on epitope regions and experimental conditions, necessitating protocol optimization.

Overall, KLF11 antibodies are critical for elucidating the protein's pathophysiological roles and its potential as a therapeutic target.

       
关键字: KLF11抗体;KLF11;KLF11 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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