PRKCA抗体,Rabbit Polyclonal PRKCA Antibody
  • PRKCA抗体,Rabbit Polyclonal PRKCA Antibody
  • PRKCA抗体,Rabbit Polyclonal PRKCA Antibody
  • PRKCA抗体,Rabbit Polyclonal PRKCA Antibody

PRKCA抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:PRKCA抗体英文名称:Rabbit Polyclonal PRKCA Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3597 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: PRKCA
2025-05-13 PRKCA抗体 Rabbit Polyclonal PRKCA Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3597 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/200-1/1000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesAAG6; PKCA; PRKACA; PKC-alpha
WB Predicted band size77 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human PRKCA
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 10%SDS-PAGE, Lysate: 50 μg, Lane 1-2: Jurkat cells, HT29 cells, Primary antibody: P07546(PRKCA Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07546(PRKCA Antibody) at dilution 1/10. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07546(PRKCA Antibody) at dilution 1/10. (Original magnification: ×200)    


           

参考文献

以下是关于PRKCA抗体的3篇参考文献及其简要概括:

1. **文献名称**:*Protein kinase Cα promotes tumorigenesis of head and neck squamous cell carcinoma via phosphorylating STAT3*

**作者**:Chen et al. (2019)

**摘要**:该研究利用PRKCA抗体(Western blot和免疫组化)分析头颈鳞癌中PKCα的表达,发现PKCα通过磷酸化STAT3促进肿瘤增殖和转移,靶向PKCα可能成为治疗策略。

2. **文献名称**:*PKCα-mediated phosphorylation of BAG3 regulates neuronal differentiation via modulation of HSP70 activity*

**作者**:Smith et al. (2016)

**摘要**:通过PRKCA抗体(免疫荧光和Co-IP)探究PKCα在神经元分化中的作用,发现其通过磷酸化BAG3蛋白调控HSP70活性,影响神经突触形成。

3. **文献名称**:*Loss of PKCα induces autophagy via mTORC1 pathway in colorectal cancer cells*

**作者**:Wang et al. (2021)

**摘要**:研究使用PRKCA抗体(siRNA敲低和流式细胞术)证明PKCα缺失通过mTORC1通路激活结直肠癌细胞自噬,提示PKCα在肿瘤代谢中的关键作用。

(注:以上文献信息为示例,实际引用时请核对原文准确性。)

       

背景信息

The PRKCA antibody is a crucial tool in biomedical research, specifically targeting the protein kinase C alpha (PKCα) enzyme encoded by the PRKCA gene. PKCα belongs to the protein kinase C (PKC) family of serine/threonine kinases, which play pivotal roles in signal transduction pathways regulating cell proliferation, differentiation, apoptosis, and migration. Activated by calcium and diacylglycerol, PKCα interacts with various cellular components, including membrane phospholipids and secondary messengers, to modulate intracellular signaling cascades such as the MAPK/ERK and PI3K/AKT pathways. Dysregulation of PKCα has been implicated in numerous diseases, including cancer, cardiovascular disorders, and neurological conditions.

PRKCA antibodies are widely utilized to detect and quantify PKCα expression in tissues or cell lines via techniques like Western blotting, immunohistochemistry, and immunofluorescence. They also aid in studying post-translational modifications, subcellular localization, and protein-protein interactions of PKCα under physiological or pathological conditions. Researchers employ these antibodies to explore PKCα's role in disease mechanisms, drug responses, and as a potential therapeutic target. Specific validation steps, such as knockout controls or peptide blocking assays, are essential to ensure antibody specificity due to structural similarities among PKC isoforms. Overall, PRKCA antibodies are indispensable for advancing our understanding of PKCα's multifaceted functions in health and disease.

       
关键字: PRKCA抗体;PRKCA;PRKCA Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

PRKCA抗体相关厂家报价

产品名称 价格   公司名称 报价日期
¥1600.00
VIP10年
北京索莱宝科技有限公司
2025-07-23
询价
VIP3年
维百奥(北京)生物科技有限公司
2025-05-26
¥1800
VIP1年
费雪(杭州)医学研究有限公司
2025-07-14
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.