同用名/别名(Synonym)
Interferon Alpha-2; IFN-Alpha-2; Interferon Alpha-A; LeIF A; IFNA2
描述(Description)
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
纯度(Purity)
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)
生物活性(Bioactivity)
Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specificBioactivity is ≥1 ×107 units/mg.
氨基酸序列(Target Protein Sequence)
CDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
制剂(Trait)
Lyophilized after extensive dialysis against PBS pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.2.
复溶(Reconstitution)
It is recommended to redissolve in sterile deionized water.
保存条件&效期(Storage & Stability)
36 months at 2°C to 8°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution
7-10 days at 2°C to 8° C under sterile conditions after reconstitution
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
运输方式(Shipping)
The product is shipped with blue ice

生物活性(Bioactivity)
Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specificBioactivity is ≥1 ×107 units/mg.The Bioactivity of Y06301 was higher than the other competing product.

电泳(SDS-PAGE)
Recombinant Human IFN-α2b SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y06301 SDS-PAGE.
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关键字: GMP级;高纯度;批间一致;生物活性;科研专供;
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