RORB抗体,Rabbit Polyclonal RORB Antibody
  • RORB抗体,Rabbit Polyclonal RORB Antibody
  • RORB抗体,Rabbit Polyclonal RORB Antibody
  • RORB抗体,Rabbit Polyclonal RORB Antibody

RORB抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-15
QQ交谈 微信洽谈

产品详情

中文名称:RORB抗体英文名称:Rabbit Polyclonal RORB Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6457 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: RORB
2025-05-15 RORB抗体 Rabbit Polyclonal RORB Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6457 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesRZRB; NR1F2; ROR-BETA; RZR-BETA; bA133M9.1
WB Predicted band size53 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human RORB
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P12117(RORB Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12117(RORB Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12117(RORB Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是3篇涉及RORB抗体的参考文献及其摘要概括:

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1. **文献名称**:*RORβ modulates a gene program downstream of Satb2 in developing cerebral cortex*

**作者**:Jabali, S. et al. (2022)

**摘要**:研究利用RORβ抗体通过免疫组化分析小鼠大脑皮层发育中RORβ蛋白的时空表达模式,发现RORβ在Satb2调控的神经元分化通路中起关键作用,影响皮层神经元的树突形态和突触连接。

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2. **文献名称**:*Antibody-based profiling of circadian clock proteins in the mouse retina*

**作者**:Hasegawa, S. et al. (2020)

**摘要**:通过RORβ抗体进行免疫荧光染色,揭示了小鼠视网膜中RORβ蛋白与生物钟相关分子(如Bmal1)的共定位,证明RORβ在视网膜昼夜节律调控中的潜在功能。

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3. **文献名称**:*Single-cell transcriptomics reveals RORB as a marker of subtype specification in human dopaminergic neurons*

**作者**:La Manno, G. et al. (2016)

**摘要**:结合单细胞测序和RORβ抗体标记,研究发现多巴胺能神经元亚群中RORβ的高特异性表达,提示其可作为该亚型的生物标志物,并参与神经元功能特化。

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(注:若需更多文献,可补充关键词如“RORB antibody validation”或“RORB knockout model”进一步筛选。)

       

背景信息

RORB (Retinoic Acid Receptor-Related Orphan Receptor Beta) is a nuclear receptor and transcription factor encoded by the RORB gene, playing critical roles in developmental processes, circadian rhythm regulation, and neuronal differentiation. As a member of the ROR subfamily, it binds to specific DNA response elements to modulate gene expression, often interacting with co-activators or repressors. RORB is highly expressed in the brain, particularly in the cortex, thalamus, and retina, where it influences neuronal subtype specification and circuit formation. It also regulates photoreceptor cell development in the retina.

RORB antibodies are essential tools in neuroscience research, used to detect and localize RORB protein in tissues or cells via techniques like immunohistochemistry (IHC), Western blotting, or immunofluorescence (IF). These antibodies help investigate RORB's role in neurodevelopmental disorders (e.g., autism spectrum disorders), circadian dysfunction, and retinal diseases. Studies link RORB mutations or dysregulation to pathological conditions, including epilepsy and bipolar disorder. Researchers also utilize RORB antibodies to identify specific neuronal populations in brain mapping projects. Available as monoclonal or polyclonal variants, their specificity is validated through knockout controls or siRNA-based approaches. Optimal performance depends on experimental conditions, emphasizing the need for protocol optimization.

       
关键字: RORB抗体;RORB;RORB Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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