UBE2T抗体,Rabbit Polyclonal UBE2T Antibody
  • UBE2T抗体,Rabbit Polyclonal UBE2T Antibody
  • UBE2T抗体,Rabbit Polyclonal UBE2T Antibody
  • UBE2T抗体,Rabbit Polyclonal UBE2T Antibody

UBE2T抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-16
QQ交谈 微信洽谈

产品详情

中文名称:UBE2T抗体英文名称:Rabbit Polyclonal UBE2T Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2206 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: UBE2T
2025-05-16 UBE2T抗体 Rabbit Polyclonal UBE2T Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2206 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesFANCT; PIG50; HSPC150
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P02338(UBE2T Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是3篇关于UBE2T抗体的模拟参考文献(注:以下内容为示例,实际文献请通过学术数据库检索验证):

---

1. **文献名称**: *UBE2T Expression Correlates with Poor Prognosis in Hepatocellular Carcinoma*

**作者**: Li X, Zhang Y, Chen R

**摘要**: 本研究利用UBE2T抗体进行免疫组化分析,发现UBE2T在肝癌组织中高表达,且与患者生存期缩短显著相关。机制研究表明UBE2T通过调控Wnt/β-catenin通路促进肿瘤侵袭。

---

2. **文献名称**: *UBE2T Antibody-Based Detection of Fanconi Anemia Pathway Dysregulation*

**作者**: Thompson S, et al.

**摘要**: 通过UBE2T特异性抗体进行Western blot和免疫荧光实验,揭示了UBE2T在范可尼贫血(Fanconi anemia)患者细胞中的功能缺失,导致DNA修复缺陷和染色体不稳定性。

---

3. **文献名称**: *Targeting UBE2T as a Therapeutic Strategy in BRCA1-Deficient Cancers*

**作者**: Wang H, et al.

**摘要**: 使用UBE2T敲低模型和抗体验证实验,证明抑制UBE2T可选择性杀伤BRCA1突变型乳腺癌细胞,提示其作为合成致死疗法的潜在靶点。

---

如需具体文献,建议通过PubMed、Google Scholar等平台检索关键词“UBE2T antibody”或“UBE2T function”。

       

背景信息

UBE2T (Ubiquitin-conjugating enzyme E2 T) is a member of the E2 ubiquitin-conjugating enzyme family, which plays a critical role in the ubiquitination cascade by transferring ubiquitin to target proteins in collaboration with E3 ligases. It is particularly notable for its involvement in the Fanconi anemia (FA) DNA repair pathway, where it interacts with FANCL, the E3 ligase component of the FA core complex. UBE2T-mediated ubiquitination of FANCD2 and FANCI is essential for activating the FA pathway, enabling repair of DNA interstrand crosslinks and maintaining genomic stability. Dysregulation of UBE2T has been linked to Fanconi anemia-related disorders and cancer, with studies showing its overexpression in various malignancies, including breast, liver, and lung cancers, where it may promote genomic instability and tumor progression.

Antibodies targeting UBE2T are vital tools for studying its expression, localization, and functional roles. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to assess UBE2T protein levels in cellular and tissue samples. Researchers also employ UBE2T-specific antibodies for co-immunoprecipitation assays to explore its interactions with pathway partners, such as FANCL or FANCD2. Additionally, these reagents help investigate UBE2T's post-translational modifications and its involvement in cellular stress responses. Given UBE2T's emerging role as a potential biomarker or therapeutic target in cancer, reliable antibodies are crucial for both basic research and clinical applications aimed at understanding disease mechanisms or developing targeted therapies.

       
关键字: UBE2T抗体;UBE2T;UBE2T Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

UBE2T抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1950
VIP4年
上海沪震实业有限公司
2026-02-09
¥960.00
VIP10年
北京索莱宝科技有限公司
2026-02-10
询价
上海华盈生物医药科技有限公司
2026-02-15
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.