**Background of FSTL5 Antibody**
FSTL5 (Follistatin-like 5) is a secreted glycoprotein belonging to the follistatin family, characterized by its follistatin-like domains and involvement in regulating cellular processes such as differentiation, adhesion, and signaling. While its exact biological functions remain under investigation, FSTL5 is implicated in developmental pathways, tissue homeostasis, and disease contexts, including cancer and neurological disorders. Studies suggest interactions with extracellular matrix components or cell surface receptors, potentially modulating pathways like TGF-β/BMP signaling.
FSTL5 antibodies are immunological tools designed to detect and study the expression, localization, and function of the FSTL5 protein. These antibodies, often monoclonal or polyclonal, are validated for applications such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and ELISA. Their development enables researchers to explore FSTL5's role in normal physiology and pathology. For instance, elevated FSTL5 levels have been observed in certain cancers, linking it to tumor progression or metastasis. In neuroscience, FSTL5 may influence neural development or synaptic plasticity.
The specificity and sensitivity of FSTL5 antibodies are critical for accurate research outcomes, requiring rigorous validation against controls. Ongoing studies aim to clarify FSTL5's mechanistic contributions and its potential as a therapeutic target or biomarker. As such, FSTL5 antibodies serve as essential reagents in advancing molecular and clinical understanding of this protein.