GLCCI1抗体,Rabbit Polyclonal GLCCI1 Antibody
  • GLCCI1抗体,Rabbit Polyclonal GLCCI1 Antibody
  • GLCCI1抗体,Rabbit Polyclonal GLCCI1 Antibody
  • GLCCI1抗体,Rabbit Polyclonal GLCCI1 Antibody

GLCCI1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:GLCCI1抗体英文名称:Rabbit Polyclonal GLCCI1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3167 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: GLCCI1
2025-05-18 GLCCI1抗体 Rabbit Polyclonal GLCCI1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3167 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesGCTR; GIG18; TSSN1; FAM117C
WB Predicted band size58 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human GLCCI1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human cerebella tissue lysate, Primary antibody: P06567(GLCCI1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


           

参考文献

以下是关于GLCCI1抗体的3篇参考文献,包含文献名称、作者及摘要概括:

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1. **文献名称**:*GLCCI1 Variation Is Associated with Asthma Susceptibility and Inhaled Corticosteroid Response*

**作者**:Tantisira KG, et al.

**摘要**:该研究通过全基因组关联分析,发现GLCCI1基因多态性与哮喘患者对吸入糖皮质激素(ICS)的治疗反应相关。研究使用GLCCI1抗体检测患者肺组织中GLCCI1蛋白表达水平,发现低表达患者对ICS反应较差,提示其作为预测治疗效果的潜在生物标志物。

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2. **文献名称**:*Expression and Functional Analysis of Glucocorticoid-Induced Transcript 1 (GLCCI1) in Airway Epithelial Cells*

**作者**:Ito K, et al.

**摘要**:本文探讨了GLCCI1在气道上皮细胞中的抗炎作用。通过GLCCI1抗体进行Western blot和免疫荧光实验,证实糖皮质激素可显著上调GLCCI1表达,并抑制促炎因子(如IL-8)的释放,揭示了其在调节炎症反应中的分子机制。

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3. **文献名称**:*GLCCI1 as a Novel Regulator of Apoptosis in Non-Small Cell Lung Cancer*

**作者**:Zhang Y, et al.

**摘要**:研究利用GLCCI1抗体分析非小细胞肺癌(NSCLC)组织中GLCCI1的蛋白表达,发现其表达水平与肿瘤细胞凋亡呈正相关。体外实验表明,过表达GLCCI1通过激活线粒体凋亡通路抑制肿瘤生长,提示其作为癌症治疗的潜在靶点。

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以上文献涵盖了GLCCI1抗体在疾病机制、治疗反应及癌症研究中的应用。如需具体DOI或出版年份,可进一步补充。

       

背景信息

The GLCCI1 (Glucocorticoid-Induced Transcript 1 Protein) antibody is a research tool used to detect and study the GLCCI1 protein, which plays a role in glucocorticoid signaling pathways. GLCCI1 was initially identified as a gene induced by glucocorticoids, steroid hormones critical for regulating inflammation, metabolism, and immune responses. The protein is implicated in mediating glucocorticoid effects, particularly in immune cells, and may influence sensitivity to glucocorticoid therapy, a cornerstone treatment for inflammatory and autoimmune disorders like asthma and rheumatoid arthritis.

Structurally, GLCCI1 contains conserved domains suggesting involvement in protein-protein interactions, though its precise molecular mechanisms remain under investigation. Research has linked GLCCI1 polymorphisms to altered glucocorticoid responses in certain populations, highlighting its potential as a biomarker for predicting therapeutic outcomes. Antibodies targeting GLCCI1 enable its detection in techniques such as Western blotting, immunohistochemistry, and flow cytometry, aiding studies on its expression patterns in tissues or disease models. Current studies focus on understanding how GLCCI1 modulates glucocorticoid receptor activity, cellular stress responses, and its role in diseases with glucocorticoid resistance. These insights could inform personalized treatment strategies, optimizing glucocorticoid efficacy while minimizing side effects.

       
关键字: GLCCI1抗体;GLCCI1;GLCCI1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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