RPS27抗体,Rabbit Polyclonal RPS27 Antibody
  • RPS27抗体,Rabbit Polyclonal RPS27 Antibody
  • RPS27抗体,Rabbit Polyclonal RPS27 Antibody
  • RPS27抗体,Rabbit Polyclonal RPS27 Antibody

RPS27抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:RPS27抗体英文名称:Rabbit Polyclonal RPS27 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3309 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: RPS27
2025-05-18 RPS27抗体 Rabbit Polyclonal RPS27 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3309 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesS27; MPS1; MPS-1
WB Predicted band size9 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human RPS27
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Jurkat cells, K562 cells, Raji cells, Primary antibody: P06948(RPS27 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P06948(RPS27 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06948(RPS27 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于RPS27抗体的3篇参考文献的简要总结:

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1. **文献名称**: "RPS27 interacts with TRIM21 to promote colorectal cancer progression by enhancing Wnt/β-catenin signaling"

**作者**: Li Y, et al.

**摘要**: 该研究利用RPS27抗体进行免疫共沉淀和Western blot分析,揭示了RPS27通过结合TRIM21调控Wnt/β-catenin信号通路,促进结直肠癌细胞的增殖和转移。

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2. **文献名称**: "Ubiquitin-like protein fusion degradation of RPS27 in Alzheimer's disease"

**作者**: Smith J, et al.

**摘要**: 研究通过免疫组化(使用RPS27抗体)发现阿尔茨海默病患者脑组织中RPS27异常聚集,其降解与泛素化通路失调相关,提示其参与神经退行性病变机制。

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3. **文献名称**: "Development of a monoclonal antibody specific to RPS27 and its application in hepatocellular carcinoma diagnosis"

**作者**: Wang H, et al.

**摘要**: 该团队开发了一种高特异性的RPS27单克隆抗体,验证其在肝细胞癌组织中的高表达,并证明其作为潜在生物标志物用于临床诊断的价值。

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(注:上述文献为虚拟示例,实际研究中建议通过PubMed或Web of Science以“RPS27 antibody”为关键词检索最新论文。)

       

背景信息

The RPS27 antibody is a research tool designed to detect and analyze the Ribosomal Protein S27 (RPS27), a component of the 40S ribosomal subunit involved in protein synthesis. RPS27. also known as Metallopanstimulin-1 (MPS-1), plays dual roles in cellular processes. Beyond its canonical function in ribosome assembly and translation, RPS27 has been implicated in DNA repair, redox regulation, and cell proliferation, with studies linking its overexpression to cancers such as hepatocellular carcinoma, breast cancer, and leukemia. This has spurred interest in RPS27 as a potential biomarker or therapeutic target.

RPS27 antibodies are widely used in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry to study protein expression, localization, and interactions. Polyclonal and monoclonal variants are available, often validated for specificity using knockout or knockdown controls. Researchers employ these antibodies to explore RPS27's role in tumorigenesis, drug resistance, and cellular stress responses. Recent studies also investigate its involvement in non-canonical pathways, including p53 modulation and ubiquitin-like post-translational modifications.

Commercial RPS27 antibodies are typically raised against epitopes in human or mouse RPS27. with cross-reactivity varying by species. Proper validation remains critical due to occasional off-target binding. Overall, RPS27 antibodies serve as essential tools for unraveling the multifaceted biology of this ribosomal protein in health and disease.

       
关键字: RPS27抗体;RPS27;RPS27 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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