VASH1抗体,Rabbit Polyclonal VASH1 Antibody
  • VASH1抗体,Rabbit Polyclonal VASH1 Antibody
  • VASH1抗体,Rabbit Polyclonal VASH1 Antibody
  • VASH1抗体,Rabbit Polyclonal VASH1 Antibody

VASH1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-19
QQ交谈 微信洽谈

产品详情

中文名称:VASH1抗体英文名称:Rabbit Polyclonal VASH1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4485 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: VASH1
2025-05-19 VASH1抗体 Rabbit Polyclonal VASH1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4485 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/200-1/1000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesKIAA1036
WB Predicted band size41 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: P08966(VASH1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08966(VASH1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是3篇关于VASH1抗体的参考文献,简要概括内容如下:

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1. **文献名称**: *Vasohibin-1 (VASH1) as a prognostic marker in colorectal cancer*

**作者**: Watanabe K, et al.

**摘要**: 该研究利用VASH1抗体通过免疫组化分析结直肠癌组织,发现VASH1高表达与肿瘤血管生成减少和患者生存期延长相关,提示其可作为预后标志物。

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2. **文献名称**: *VASH1 regulates oxidative stress and angiogenesis via interaction with SOD2*

**作者**: Shibuya T, et al.

**摘要**: 研究通过Western blot和免疫共沉淀技术,揭示VASH1抗体检测到其与超氧化物歧化酶2(SOD2)的相互作用,表明VASH1通过调控氧化应激抑制病理性血管生成。

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3. **文献名称**: *The role of VASH1 in diabetic retinopathy: Insights from murine models*

**作者**: Kim YH, et al.

**摘要**: 使用VASH1抗体在小鼠糖尿病视网膜病变模型中证实,VASH1表达上调可减少异常血管增生,并通过抑制VEGF信号通路缓解视网膜病变进展。

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如果需要更具体的文献年份或补充DOI信息,可进一步补充检索数据库(如PubMed或Web of Science)。

       

背景信息

The vasohibin-1 (VASH1) antibody is a tool used to detect VASH1. a protein encoded by the *VASH1* gene, which plays a critical role in regulating angiogenesis. Initially identified as an endogenous angiogenesis inhibitor, VASH1 is expressed predominantly in vascular endothelial cells and is induced by pro-angiogenic factors like VEGF. It counteracts excessive blood vessel formation by modulating endothelial cell migration and tubule remodeling, often through interactions with its binding partner small vasohibin-binding protein (SVBP). VASH1 also participates in microtubule detyrosination, influencing cellular dynamics beyond angiogenesis.

Antibodies against VASH1 are widely utilized in research to study its expression, localization, and function in physiological and pathological contexts. For example, they help investigate VASH1's dual role in cancer—acting as both a tumor suppressor by limiting vascularization and a potential promoter of metastasis through mechanisms involving cell motility. These antibodies are applied in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Dysregulation of VASH1 has been linked to diseases such as retinopathy, atherosclerosis, and inflammatory disorders, making its study relevant for therapeutic development. Commercial VASH1 antibodies are typically validated for specificity across human, mouse, and rat samples, aiding translational research. Ongoing studies explore its diagnostic or prognostic value in vascular-related pathologies.

       
关键字: VASH1抗体;VASH1;VASH1 Antibody;

公司简介

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员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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