CPT1B抗体,Rabbit Polyclonal CPT1B Antibody
  • CPT1B抗体,Rabbit Polyclonal CPT1B Antibody
  • CPT1B抗体,Rabbit Polyclonal CPT1B Antibody
  • CPT1B抗体,Rabbit Polyclonal CPT1B Antibody

CPT1B抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:CPT1B抗体英文名称:Rabbit Polyclonal CPT1B Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4915 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CPT1B
2025-05-20 CPT1B抗体 Rabbit Polyclonal CPT1B Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4915 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCPTI; CPT1M; MCPT1; CPT1-M; CPTI-M; M-CPT1; MCCPT1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CPT1B
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09565(CPT1B Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P09565(CPT1B Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是3-4条关于CPT1B抗体的参考文献示例(内容基于模拟生成,非真实文献):

1. **名称**:*"Characterization of CPT1B antibody specificity in skeletal muscle metabolism"*

**作者**:Lee, J. et al. (2018)

**摘要**:本研究验证了一种高特异性CPT1B抗体在人和小鼠骨骼肌组织中的应用,通过免疫印迹和免疫组化证实其识别线粒体膜上的CPT1B蛋白,并揭示其在脂肪酸氧化调控中的作用。

2. **名称**:*"CPT1B deficiency in cardiac ischemia-reperfusion injury: Insights from antibody-based detection"*

**作者**:Smith, R. & Zhang, H. (2020)

**摘要**:利用CPT1B特异性抗体,研究发现心脏缺血再灌注损伤模型中CPT1B表达显著下调,提示其可能通过影响线粒体脂肪酸代谢加重心肌损伤。

3. **名称**:*"Development of a novel monoclonal antibody for human CPT1B and its application in obesity research"*

**作者**:Garcia, M. et al. (2021)

**摘要**:报道了一种新型单克隆CPT1B抗体的开发,并在肥胖患者肌肉组织中验证其应用,发现CPT1B蛋白水平与胰岛素抵抗呈负相关。

4. **名称**:*"CPT1B antibody reveals exercise-induced mitochondrial adaptation in skeletal muscle"*

**作者**:Wang, Y. et al. (2019)

**摘要**:通过CPT1B抗体检测,证明长期有氧运动上调骨骼肌线粒体CPT1B表达,增强脂肪酸氧化能力,为代谢疾病治疗提供依据。

(注:以上文献为示例性内容,实际引用请查询PubMed或SciFinder等数据库获取真实文献。)

       

背景信息

The CPT1B antibody is a crucial tool for studying carnitine palmitoyltransferase 1B (CPT1B), a mitochondrial enzyme central to fatty acid metabolism. CPT1B, one of three CPT1 isoforms (CPT1A, CPT1B, CPT1C), is predominantly expressed in skeletal muscle and heart tissues. It catalyzes the rate-limiting step of fatty acid β-oxidation by transferring long-chain fatty acids into mitochondria, a process vital for energy production during fasting or prolonged exercise. Dysregulation of CPT1B is linked to metabolic disorders, including obesity, insulin resistance, and cardiovascular diseases, making it a target for metabolic research.

CPT1B antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression, localization, and tissue-specific distribution. They help investigate CPT1B’s role in metabolic adaptations, such as exercise-induced changes or dietary interventions. Researchers also employ these antibodies to explore pathological conditions, such as cancer (where altered lipid metabolism supports tumor growth) or muscle-related metabolic syndromes. Specificity validation (e.g., knockout controls) is critical due to structural similarities among CPT1 isoforms. Commercial CPT1B antibodies are typically raised against unique epitopes in the N-terminal or C-terminal regions, with host species varying (rabbit, mouse). Their applications extend to preclinical studies targeting CPT1B for therapeutic modulation in metabolic diseases.

       
关键字: CPT1B抗体;CPT1B;CPT1B Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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