MAP1B 抗体,Rabbit Polyclonal MAP1B Antibody
  • MAP1B 抗体,Rabbit Polyclonal MAP1B Antibody
  • MAP1B 抗体,Rabbit Polyclonal MAP1B Antibody
  • MAP1B 抗体,Rabbit Polyclonal MAP1B Antibody

MAP1B 抗体;MAP1B Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-25
QQ交谈 微信洽谈

产品详情

中文名称:MAP1B 抗体英文名称:Rabbit Polyclonal MAP1B Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6025 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: MAP1B
2025-05-25 MAP1B 抗体 Rabbit Polyclonal MAP1B Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6025 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/3000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesMAP5; FUTSCH
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human MAP1B
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11374(MAP1B  Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11374(MAP1B  Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于MAP1B抗体的3篇参考文献及简要摘要:

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1. **文献名称**: "Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development in hippocampal neurons"

**作者**: Tortosa E. et al.

**摘要**: 该研究利用MAP1B特异性抗体结合免疫荧光技术,证明MAP1B通过调节微管稳定性影响海马神经元树突棘的形态发生,并揭示其在突触可塑性中的潜在作用。

2. **文献名称**: "MAP1B phosphorylation is critical for axonal regeneration in mature neurons"

**作者**: Barnat M. et al.

**摘要**: 文章通过Western blot和免疫组化分析,使用MAP1B抗体发现其磷酸化状态调控成熟神经元轴突再生能力,为神经损伤修复研究提供了新靶点。

3. **文献名称**: "Characterization of a monoclonal antibody to microtubule-associated protein 1B (MAP1B): Distinct phosphorylation states in developing brain"

**作者**: Sato-Yoshitake R. et al.

**摘要**: 该文献描述了一种特异性识别MAP1B的单克隆抗体的开发,并验证其在发育中大脑不同区域检测MAP1B磷酸化动态变化的有效性,揭示了其在神经发育中的时空表达模式。

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以上文献均聚焦于MAP1B抗体的应用及其在神经元结构与功能研究中的关键作用。

       

背景信息

The microtubule-associated protein 1B (MAP1B) is a cytoskeletal protein critical for neuronal development and synaptic plasticity. It belongs to the MAP family, which stabilizes microtubules and regulates their dynamics. MAP1B is highly expressed during early brain development, playing key roles in axonal elongation, growth cone guidance, and dendritic arborization. Its activity is modulated by phosphorylation, which influences microtubule stability and interactions with other cytoskeletal components. In mature neurons, MAP1B remains involved in maintaining structural integrity and modulating synaptic function.

MAP1B antibodies are essential tools for studying its expression, localization, and post-translational modifications. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to investigate MAP1B's roles in neurodevelopment, neurodegeneration (e.g., Alzheimer’s disease), and axonal regeneration. Some antibodies specifically target phosphorylated isoforms, enabling research into signaling pathways regulating MAP1B activity. Dysregulation of MAP1B has been linked to neurological disorders, making these antibodies valuable for both basic research and clinical diagnostics.

       
关键字: MAP1B 抗体;MAP1B ;MAP1B Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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