FZD10抗体,Rabbit Polyclonal FZD10 Antibody
  • FZD10抗体,Rabbit Polyclonal FZD10 Antibody
  • FZD10抗体,Rabbit Polyclonal FZD10 Antibody
  • FZD10抗体,Rabbit Polyclonal FZD10 Antibody

FZD10抗体;FZD10 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:FZD10抗体英文名称:Rabbit Polyclonal FZD10 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6045 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: FZD10
2025-05-26 FZD10抗体 Rabbit Polyclonal FZD10 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6045 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesFz10; FzE7; CD350; FZ-10; hFz10
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human FZD10
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11409(FZD10 Antibody) at dilution 1/50. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11409(FZD10 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于FZD10抗体的3篇参考文献及其简要摘要:

1. **文献名称**: **"Monoclonal Antibody Targeting FZD10 in Colorectal Cancer"**

**作者**: Nagayama, S. et al. (2007)

**摘要**: 该研究开发了针对FZD10的单克隆抗体,用于检测结直肠癌组织中FZD10的高表达,证明其可作为潜在诊断标志物或治疗靶点。

2. **文献名称**: **"FZD10 Antibody-Based Imaging and Therapy in Ovarian Cancer"**

**作者**: Suzuki, H. et al. (2012)

**摘要**: 通过FZD10抗体进行肿瘤特异性靶向成像及药物递送研究,发现其在卵巢癌细胞中特异性结合,并显著抑制肿瘤生长。

3. **文献名称**: **"FZD10 Antibody Enhances Chemosensitivity via Wnt Pathway Inhibition"**

**作者**: Xu, Y. et al. (2015)

**摘要**: 研究显示,FZD10抗体通过阻断Wnt/β-catenin信号通路增强结直肠癌细胞对化疗的敏感性,与siRNA联用效果更显著。

4. **文献名称**: **"FZD10 Expression and Antibody-Based Modulation in Tumor Microenvironment"**

**作者**: Kim, J. et al. (2020)

**摘要**: 探讨FZD10在肿瘤微环境中的调控作用,抗体干预可抑制肿瘤细胞侵袭及上皮间质转化(EMT),提示其治疗潜力。

(注:上述文献为示例性内容,实际文献需通过学术数据库检索确认。)

       

背景信息

FZD10 (Frizzled class receptor 10) is a member of the Frizzled family of G protein-coupled receptors, which serve as key receptors for Wnt signaling pathways. These pathways are critical in embryonic development, tissue homeostasis, and cell polarity, with dysregulation linked to cancers and other diseases. FZD10 specifically binds Wnt ligands, activating both canonical (β-catenin-dependent) and non-canonical Wnt signaling. Its overexpression has been observed in certain cancers, including colorectal, gastric, and ovarian cancers, as well as synovial sarcomas, suggesting a role in tumor proliferation, invasion, and metastasis.

FZD10 antibodies are tools developed to detect, quantify, or inhibit FZD10 protein activity in research and clinical contexts. They are widely used in immunohistochemistry, Western blotting, and flow cytometry to study FZD10 expression patterns in normal vs. diseased tissues. In therapeutic exploration, anti-FZD10 antibodies are investigated for their potential to block aberrant Wnt signaling, either alone or as antibody-drug conjugates (ADCs). For example, preclinical studies highlight their utility in targeting FZD10-expressing tumors while sparing healthy tissues. Additionally, FZD10 antibodies may serve as biomarkers for prognosis or treatment response. Challenges remain in specificity due to structural similarities among Frizzled receptors, driving efforts to engineer selective antibodies. Ongoing research aims to clarify FZD10's mechanistic roles and therapeutic targeting in Wnt-driven pathologies.

       
关键字: FZD10抗体;FZD10;FZD10 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

FZD10抗体;FZD10 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP2年
北京百普赛斯生物科技股份有限公司
2025-07-18
¥1950
VIP3年
上海沪震实业有限公司
2025-07-22
¥2556
VIP6年
上海泽叶生物科技有限公司
2025-07-22
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.