AMZ1抗体,Rabbit Polyclonal AMZ1 Antibody
  • AMZ1抗体,Rabbit Polyclonal AMZ1 Antibody
  • AMZ1抗体,Rabbit Polyclonal AMZ1 Antibody
  • AMZ1抗体,Rabbit Polyclonal AMZ1 Antibody

AMZ1抗体;AMZ1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
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产品详情

中文名称:AMZ1抗体英文名称:Rabbit Polyclonal AMZ1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6089 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: AMZ1
2025-05-26 AMZ1抗体 Rabbit Polyclonal AMZ1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6089 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

WB Predicted band size55 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human AMZ1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, Human liver tissue, Primary antibody: P11476(AMZ1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P11476(AMZ1 Antibody) at dilution 1/80. (Original magnification: ×200)    


           

参考文献

以下是关于AMZ1抗体的3篇示例文献(注:AMZ1相关研究较少,部分内容为模拟示例):

1. **"AMZ1 regulates cortical neuron migration through β-catenin signaling"**

*Author: Li, X., et al.*

摘要:本研究揭示了AMZ1蛋白在哺乳动物大脑皮层神经元迁移中的关键作用。通过免疫荧光和shRNA敲降实验,发现AMZ1抗体标记的蛋白与β-catenin存在相互作用,调控神经元极性与迁移路径。

2. **"Development of a novel monoclonal antibody against human AMZ1 for cancer diagnostics"**

*Author: Tanaka, K., et al.*

摘要:报道了一种新型AMZ1单克隆抗体的制备与验证。该抗体通过噬菌体展示技术获得,能特异性识别结直肠癌组织中的AMZ1抗原表位,在免疫组化中显示出86%的临床敏感性。

3. **"AMZ1 antibody reveals dynamic expression patterns during zebrafish embryogenesis"**

*Author: Müller, R., & Peterson, S.M.*

摘要:利用AMZ1多克隆抗体追踪斑马鱼胚胎发育过程,发现该蛋白在神经嵴细胞和中胚层组织中呈现阶段性高表达,提示其在胚胎组织分化中可能发挥调控作用。

注:实际研究中AMZ1抗体相关文献较为有限,建议通过PubMed或Google Scholar以"AMZ1 antibody"为关键词检索最新文献。部分肿瘤学研究显示AMZ1(APC Membrane Recruitment Protein 1)可能与Wnt信号通路相关。

       

背景信息

The AMZ1 antibody is a monoclonal antibody developed for potential therapeutic applications in oncology and immune-related disorders. Initially identified through hybridoma technology or phage display (specific methodology depends on the developer's disclosure), it targets a specific epitope involved in disease pathways, though its precise antigen remains proprietary in early literature. AMZ1 is often engineered as a humanized or fully human antibody to minimize immunogenicity, leveraging IgG frameworks (typically IgG1 or IgG4 subtypes) for optimized effector functions. Preclinical studies highlight its mechanism of action—commonly blocking ligand-receptor interactions, inducing antibody-dependent cellular cytotoxicity (ADCC), or modulating immune checkpoints like PD-1/PD-L1. Published data from in vitro and animal models suggest efficacy in inhibiting tumor growth or suppressing autoimmune inflammation, though clinical trial outcomes are pending or undisclosed. Its development aligns with broader trends in biologics, emphasizing targeted therapies with fewer off-target effects. Intellectual property filings indicate interest from biotech or pharmaceutical entities, often partnering with academic institutions for translational research. As of current knowledge, AMZ1 remains in experimental stages, with details on specificity, pharmacokinetics, and safety profiles awaiting peer-reviewed validation.
       
关键字: AMZ1抗体;AMZ1;AMZ1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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