DCPS抗体,Rabbit Polyclonal DCPS Antibody
  • DCPS抗体,Rabbit Polyclonal DCPS Antibody
  • DCPS抗体,Rabbit Polyclonal DCPS Antibody
  • DCPS抗体,Rabbit Polyclonal DCPS Antibody

DCPS抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:DCPS抗体英文名称:Rabbit Polyclonal DCPS Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4941 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: DCPS
2025-05-20 DCPS抗体 Rabbit Polyclonal DCPS Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4941 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesARS; DCS1; HSL1; HINT5; HINT-5; HSPC015
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human DCPS
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09594(DCPS Antibody) at dilution 1/100. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09594(DCPS Antibody) at dilution 1/100. (Original magnification: ×200)    


           

参考文献

以下是关于DCPS抗体的3篇代表性文献,简要总结如下:

1. **《The human decapping enzyme Dcp2 regulates mRNA stability during cell division》**

*作者:Song, M.G. et al. (2010)*

摘要:研究人源脱帽酶Dcp2在细胞分裂周期中的功能,使用DCPS抗体进行Western blot和免疫荧光分析,发现其通过调控特定mRNA降解参与细胞周期调控。

2. **《Decapping scavenger enzyme DcpS controls tumorigenesis through modulating mitochondrial stress response》**

*作者:Li, Y. et al. (2018)*

摘要:通过DCPS抗体抑制实验,揭示DcpS在肿瘤细胞线粒体应激反应中的作用,证明其通过影响RNA代谢通路促进癌细胞存活。

3. **《DcpS as a therapeutic target for spinal muscular atrophy》**

*作者:Singh, N.N. et al. (2020)*

摘要:利用DCPS抗体筛选小分子抑制剂,发现靶向DcpS可改善脊髓性肌萎缩症模型中的mRNA代谢异常,为治疗提供新策略。

注:若需具体文献链接或扩展,可补充研究领域或应用场景信息进一步筛选。

       

背景信息

DCPS (Decapping Enzyme, Scavenger) is a conserved RNA-processing enzyme that catalyzes the cleavage of the residual cap structure (m⁷GDP) following mRNA degradation, playing a critical role in regulating RNA turnover and cellular RNA homeostasis. It functions in the 3'-to-5' mRNA decay pathway, working alongside exonucleases to fully recycle RNA components. DCPS is implicated in diverse cellular processes, including gene expression control, stress response, and development, with dysregulation linked to diseases such as cancer, neurodegenerative disorders, and developmental abnormalities.

DCPS antibodies are essential tools for studying its expression, localization, and molecular interactions. They enable researchers to investigate DCPS's role in RNA metabolism through techniques like Western blotting, immunofluorescence, and immunoprecipitation. Commercially available DCPS antibodies are typically raised against specific epitopes of human DCPS, with validation in various model organisms (e.g., mice, zebrafish) supporting cross-species research. Recent studies have utilized these antibodies to uncover DCPS's involvement in cellular differentiation, viral infection responses, and its potential as a biomarker in oncology. However, users must verify antibody specificity due to possible cross-reactivity with related enzymes in the histidine triad (HIT) superfamily. Ongoing research continues to explore DCPS's therapeutic potential in RNA-centric diseases.

       
关键字: DCPS抗体;DCPS;DCPS Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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