EVL抗体,Rabbit Polyclonal EVL Antibody
  • EVL抗体,Rabbit Polyclonal EVL Antibody
  • EVL抗体,Rabbit Polyclonal EVL Antibody
  • EVL抗体,Rabbit Polyclonal EVL Antibody

EVL抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-21
QQ交谈 微信洽谈

产品详情

中文名称:EVL抗体英文名称:Rabbit Polyclonal EVL Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5535 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: EVL
2025-05-21 EVL抗体 Rabbit Polyclonal EVL Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5535 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesRNB6
WB Predicted band size45 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human EVL
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: RAMOS cell lysate, Primary antibody: P10443(EVL Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10443(EVL Antibody) at dilution 1/140. (Original magnification: ×200)    


           

参考文献

以下是关于EVL抗体的参考文献示例(内容基于领域知识概括,非真实文献):

---

1. **文献名称**:*"EVL regulates actin cytoskeleton remodeling in neuronal growth cones"*

**作者**:Miller, K.L. et al.

**摘要**:本研究利用特异性EVL抗体探究了EVL蛋白在神经元生长锥动态中的功能,发现其通过调控肌动蛋白聚合促进轴突导向,抗体验证采用免疫印迹与免疫荧光定位。

2. **文献名称**:*"Development and validation of a high-affinity monoclonal antibody for EVL detection in cancer cell lines"*

**作者**:Zhang, Y. et al.

**摘要**:报道了一种新型EVL单克隆抗体的开发,验证了其在乳腺癌细胞(MCF-7)中的特异性,证实EVL表达与细胞迁移能力正相关,适用于流式细胞术及免疫组化。

3. **文献名称**:*"Ena/VASP family protein EVL modulates T cell receptor signaling through actin reorganization"*

**作者**:Tanaka, H. et al.

**摘要**:通过EVL抗体阻断实验,揭示EVL在T细胞免疫突触形成中的作用,证明其通过稳定肌动蛋白网络增强TCR信号传导,依赖CRISPR/抗体共聚焦成像技术。

4. **文献名称**:*"Functional diversity of Ena/VASP proteins: Insights from EVL knockout models"*(综述)

**作者**:Carter, R. & Bensen, J.

**摘要**:综述总结了EVL在细胞迁移、黏附中的独特功能,对比不同Ena/VASP成员抗体应用,强调EVL抗体在胚胎发育研究中的关键作用。

---

注:以上为模拟示例,实际文献需通过学术数据库(PubMed、Web of Science)检索确认。

       

背景信息

EVL (Ena/VASP-like protein) is a member of the Ena/VASP family, which regulates actin cytoskeleton dynamics by interacting with actin filaments and modulating cell motility, adhesion, and morphogenesis. Discovered in the late 1990s, EVL shares homology with Enabled (Ena) and Vasodilator-Stimulated Phosphoprotein (VASP), featuring conserved domains like the EVH1 (Ena/VASP homology 1) and EVH2. which mediate protein-protein interactions and actin binding. EVL localizes to focal adhesions, lamellipodia, and filopodia, where it promotes actin polymerization and coordinates cell migration by antagonizing capping proteins.

EVL antibodies are vital tools for studying its role in cellular processes, including neuronal development, immune cell trafficking, and cancer metastasis. They enable detection of EVL expression, localization, and post-translational modifications (e.g., phosphorylation) via techniques like Western blotting, immunofluorescence, and immunoprecipitation. Dysregulation of EVL is linked to pathological conditions; reduced EVL levels correlate with impaired synaptic plasticity in neurological disorders, while overexpression in cancers may enhance invasive potential. Research using EVL-knockout models or CRISPR-mediated silencing further highlights its importance in embryogenesis and tissue homeostasis. Commercial EVL antibodies are typically raised against conserved epitopes, with validation in specific applications ensuring reliability. Ongoing studies aim to clarify EVL's interplay with signaling pathways (e.g., Rho GTPases) and its potential as a therapeutic target.

       
关键字: EVL抗体;EVL;EVL Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

EVL抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1800
VIP1年
上海酶联生物科技有限公司
2025-12-17
¥3384
VIP5年
上海博尔森生物科技有限公司
2025-12-29
¥2460
VIP7年
上海泽叶生物科技有限公司
2025-12-29
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.