DMAP1抗体,Rabbit Polyclonal DMAP1 Antibody
  • DMAP1抗体,Rabbit Polyclonal DMAP1 Antibody
  • DMAP1抗体,Rabbit Polyclonal DMAP1 Antibody
  • DMAP1抗体,Rabbit Polyclonal DMAP1 Antibody

DMAP1抗体;DMAP1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
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产品详情

中文名称:DMAP1抗体英文名称:Rabbit Polyclonal DMAP1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7173 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: DMAP1
2025-05-28 DMAP1抗体 Rabbit Polyclonal DMAP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7173 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesEAF2; SWC4; MEAF2; DNMAP1; DNMTAP1
WB Predicted band size53 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human DMAP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: RAW and NIH/3T3 cell lysates, Primary antibody: P13273(DMAP1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13273(DMAP1 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13273(DMAP1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于DMAP1抗体的3篇参考文献示例(注:文献为虚拟示例,仅供参考格式):

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1. **文献名称**:*DMAP1 Cooperates with HP1 Proteins to Promote Heterochromatin Assembly*

**作者**:Smith J, Doe R, Johnson A

**摘要**:通过免疫共沉淀(Co-IP)和染色质免疫沉淀(ChIP)结合DMAP1抗体,研究发现DMAP1与HP1蛋白相互作用,调控异染色质形成,影响基因沉默和基因组稳定性。

2. **文献名称**:*DMAP1 Is Essential for DNA Damage-Induced Apoptosis via Modulating p53 Acetylation*

**作者**:Chen L, Wang X, Zhang Y

**摘要**:利用DMAP1抗体进行Western blot和免疫荧光实验,揭示DMAP1通过调控p53的乙酰化修饰参与DNA损伤应答,影响细胞凋亡和肿瘤抑制功能。

3. **文献名称**:*DMAP1 Mediates Transcriptional Repression through Interaction with Histone Deacetylases*

**作者**:Yamamoto K, Sato T, Tanaka M

**摘要**:通过ChIP-seq和免疫沉淀实验(使用DMAP1抗体),证实DMAP1与组蛋白去乙酰化酶(HDACs)形成复合物,抑制靶基因转录,参与胚胎发育调控。

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**备注**:以上文献为示例,实际研究中建议通过PubMed或Google Scholar检索关键词“DMAP1 antibody”、“DMAP1 function”等获取真实文献。

       

背景信息

**Background of DMAP1 Antibody**

The DMAP1 (DNA Methyltransferase 1-Associated Protein 1) antibody is a research tool used to study the role of DMAP1. a multifunctional protein involved in chromatin remodeling, transcriptional regulation, and DNA repair. DMAP1 interacts with DNA methyltransferase 1 (DNMT1), forming part of a complex that mediates DNA methylation, a key epigenetic modification critical for gene silencing, genomic imprinting, and X-chromosome inactivation. Beyond its association with DNMT1. DMAP1 also binds to components of histone acetyltransferase (HAT) complexes, such as TIP60. linking DNA methylation to histone modification processes.

DMAP1 antibodies are widely utilized in techniques like Western blotting, immunoprecipitation, and immunofluorescence to detect DMAP1 expression, localization, and interaction partners in various biological contexts. Studies using these antibodies have revealed DMAP1's involvement in cell cycle progression, apoptosis, and response to DNA damage. Dysregulation of DMAP1 has been implicated in cancers and developmental disorders, underscoring its importance in maintaining genomic stability and proper epigenetic regulation.

By enabling precise detection of DMAP1. these antibodies contribute to advancing research on epigenetic mechanisms, cancer biology, and potential therapeutic targets.

       
关键字: DMAP1抗体;DMAP1;DMAP1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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