Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
分子别名(Synonym)
CEACAM-5,CD66e,CEA,Meconium antigen 100
表达区间及表达系统(Source)
Human CEACAM-5, His Tag (CE5-H5226) is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Ala 685 (Accession # P06731).
Predicted N-terminus: Lys 35
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 72.2 kDa. The protein migrates as 100-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method / rFC method.
纯度(Purity)
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景介绍
癌胚抗原相关细胞黏附分子5(CEACAM5)——亦称癌胚抗原(CEA)、胎便抗原100、CD抗原CD66e——隶属于免疫球蛋白超家族中的CEA家族。该蛋白包含七个免疫球蛋白样结构域,以同源二聚体形式存在。当结合大肠杆菌Dr黏附素时,该二聚体结构会发生解离。作为细胞表面糖蛋白,CEACAM5参与细胞黏附及胞内信号传导,同时也是大肠杆菌Dr黏附素的受体。
关键字: CEACAM-5;CEACAM-5蛋白;CEACAM-5重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。