Product Name:ATX-GD-59
CAS No.:N/A
Synonyms:模仿肽ATX-GD-59
Catalog No.:218P236
Brand:Typeptide Biotech(肽研生物)
Description:ATX-GD-59作为药物多肽,是一种基于肽的疗法(peptide therapy),主要生物机理是模仿抗原表位灭活攻击甲状腺的白细胞,阻止抗促甲状腺激素受体(TSHR)刺激性抗体的产生,能够靶向格雷夫斯病的免疫学基础,有望成为60年来首个治疗格雷夫斯病的修饰创新疗法。在临床上,ATX-GD-59治疗格雷夫斯病具有良好的安全性和耐受性,能偶促甲状腺激素受体(TSHR)抗体水平正常。
ATX-GD-59, as a drug peptide, is a peptide therapy based on the main biological mechanism of mimicking antigenic epitopes to inactivate white blood cells that attack the thyroid gland, preventing the production of anti thyroid stimulating hormone receptor (TSHR) stimulating antibodies. It can target the immunological basis of Graves' disease and is expected to become the first modified innovative therapy for treating Graves' disease in 60 years. In clinical practice, ATX-GD-59 has good safety and tolerability in the treatment of Graves' disease, and can occasionally promote normal levels of thyroid hormone receptor (TSHR) antibodies.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | KKKKYVSIDVTLQQLESHKKK |
Sequence(3-letter code) | H-Lys-Lys-Lys-Lys-Tyr-Val-Ser-Ile-Asp-Val-Thr-Leu-Gln-Gln-Leu-Glu-Ser-His-Lys-Lys-Lys-OH |
Peptide Structure | 
|
Molecular Formula | C114H198N32O32 |
Molecular Weight | 2529.26 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用,不得用于人体。
关键字: ATX-GD-59;模仿肽ATX-GD-59;多肽;多肽合成;ATX-GD-59 peptide th;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。