(Peresolimab)Biosimilar Reference Antibody-GS40543 新品

货号：GS40543

Peresolimab (also known as LY3462817) is an investigational, humanized IgG1 monoclonal antibody developed by Eli Lilly and Company. It targets the programmed cell death‑1 (PD‑1) pathway, specifically binding to the PD‑1 receptor on immune cells. By blocking the interaction between PD‑1 and its ligands (PD‑L1/PD‑L2), it reverses PD‑1‑mediated immunosuppression, thereby restoring and enhancing T‑cell‑mediated anti‑tumor immune responses. As an IgG1 isotype, it is designed to potentially engage immune effector functions. It is being evaluated as an immune checkpoint inhibitor for the treatment of advanced solid tumors.