货号:GS40176
Denintuzumab mafodotin (also known as SGN-CD19A) is an investigational antibody-drug conjugate (ADC) developed for the treatment of B-cell malignancies. It combines a humanized monoclonal antibody with a potent cytotoxic payload to target cells expressing CD19, a hallmark antigen of B-lineage cells. Clinical trials have evaluated its efficacy in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL), aiming to provide a targeted therapeutic option for these aggressive diseases.
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