(Denosumab)Biosimilar Reference Antibody-GS40177

货号：GS40177

Denosumab is a fully human monoclonal antibody used to treat conditions involving excessive bone resorption. Marketed under the brand names Prolia® and Xgeva®, it is approved for multiple indications: postmenopausal osteoporosis, bone loss from hormone ablation in prostate or breast cancer, giant cell tumor of bone, hypercalcemia of malignancy, and to prevent skeletal-related events (such as fractures) in patients with bone metastases from solid tumors. It is administered via subcutaneous injection and works by potently inhibiting osteoclast-mediated bone breakdown.