货号:GS40345
Iscalimab (CFZ533) is a fully human monoclonal antibody developed by Novartis. It functions as an immunosuppressant by selectively blocking the CD40 protein on immune cells, thereby inhibiting a key pathway involved in T-cell activation and antibody production. It has been investigated primarily in solid organ transplantation and various autoimmune diseases, such as primary Sjögren's syndrome and Graves' ophthalmopathy.
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