货号:GS40749
Tucotuzumab is a humanized monoclonal antibody targeting epithelial cell adhesion molecule (EpCAM, also known as CD326), a glycoprotein overexpressed on many epithelial carcinomas. It binds to EpCAM to inhibit tumor cell adhesion, migration, and metastasis, and may also engage immune effector functions. It has been investigated for the treatment of solid tumors such as ovarian, colorectal, and pancreatic cancers.
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