Chemical Safety Data Sheet MSDS / SDS
2-Chloroethanol
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: 2-Chloroethanol
- CBnumber: CB6111920
- CAS: 107-07-3
- EINECS Number: 203-459-7
- Synonyms: ETHYLENE CHLOROHYDRIN;2-chloroethan-1-ol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
Hazard statements
H330 Fatal if inhaled
H310 Fatal in contact with skin
H300 Fatal if swallowed
H226 Flammable liquid and vapour
Substance
- Product name: 2-Chloroethanol
- Synonyms: ETHYLENE CHLOROHYDRIN;2-chloroethan-1-ol
- CAS: 107-07-3
- EC number: 203-459-7
- MF: C2H5ClO
- MW: 80.51
4.1 Description of first-aid measures
General adviceFirst aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
Remove contact lenses.
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately.
In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.
In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Hydrogen chloride gas
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
Hydrogen chloride gas
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
4
2
0
| HEALTH | 4 | Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsNo metal containers.
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Moisture sensitive.
Storage class
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Moisture sensitive.
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['2-chloroethanol', '107-07-3', 'MAC', '2 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', 'Remarks', 'Skin', None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Viton®
Minimum layer thickness: 0.7 mm
Break through time: 480 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Chloroprene
Minimum layer thickness: 0.65 mm
Break through time: 10 min
Material tested:KCL 720 Camapren®
Internet: www.kcl.de).
Full contact
Material: Viton®
Minimum layer thickness: 0.7 mm
Break through time: 480 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Chloroprene
Minimum layer thickness: 0.65 mm
Break through time: 10 min
Material tested:KCL 720 Camapren®
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid, clear
- b) Colorcolorless
- c) OdorFaint, ethereal.
- d) Melting point/freezing pointMelting point/range: -89 °C - lit.
- e) Initial boiling point and boiling range129 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 16 %(V)
Lower explosion limit: 5 %(V) - h) Flash point55 °C - closed cup
- i) Autoignition temperature425 °C
- j) Decomposition temperatureNo data available
- k) pH6-7 (20°C, 500g/L in H2O)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubilityat 20 °C completely miscible
- n) Partition coefficient n-octanol/waterlog Pow: 1.06 at 20 °C - Bioaccumulation is not expected.
- o) Vapor pressure7 hPa at 20 °C 47 hPa at 55 °C
- p) Density1.201 g/cm3 at 25 °C - lit.
- Relative density1.201 g/mL at 25 °C(lit.)
- q) Relative vapor density2.78 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- SolubilitySoluble in alcohol (Weast, 1986)
- Dielectric constant26.0（25℃）
9.2 Other safety information
Relative vapor density2.78 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
Alkali metals
Alkaline earth metals chlorosulfonic acid
Amines amides
Strong oxidizing agents
Sodium hydroxide alkalines
Alkali metals
Alkaline earth metals chlorosulfonic acid
Amines amides
Strong oxidizing agents
Sodium hydroxide alkalines
10.3 Conditions to avoid
Heating.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityAcute toxicity estimate Oral - 5.1 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: Irritation of mucous membranes, Risk of aspiration upon vomiting., Aspiration may cause pulmonary edema and pneumonitis.
Oral: Rapid absorption.
LC50 Inhalation - Rat - male and female - 4 h - 0.1 mg/l - vapor (OECD Test Guideline 403)
LD50 Dermal - Mouse - 18 mg/kg
Remarks: (RTECS)
Skin corrosion/irritation
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: Irritation of mucous membranes, Risk of aspiration upon vomiting., Aspiration may cause pulmonary edema and pneumonitis.
Oral: Rapid absorption.
LC50 Inhalation - Rat - male and female - 4 h - 0.1 mg/l - vapor (OECD Test Guideline 403)
LD50 Dermal - Mouse - 18 mg/kg
Remarks: (RTECS)
Skin - Rabbit
Result: No skin irritation - 2 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: No skin irritation - 2 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: Causes serious eye damage. - 24 h (OECD Test Guideline 405)
Respiratory or skin sensitization
Result: Causes serious eye damage. - 24 h (OECD Test Guideline 405)
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 429)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: mitotic recombination assay
Test system: Saccharomyces cerevisiae
Metabolic activation: with and without metabolic activation
Result: negative
Remarks: (ECHA)
Test Type: gene mutation test
Test system: S. pombe
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 480
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Metabolic activation: Metabolic activation
Method: OECD Test Guideline 473
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 479
Result: positive
Test Type: In vivo micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Test Type: dominant lethal test
Species: Mouse
Application Route: Oral
Method: OECD Test Guideline 478
Result: negative
Test Type: in vivo assay
Species: Drosophila melanogaster
Cell type: sperm
Application Route: Oral
Method: OECD Test Guideline 477
Result: negative
Carcinogenicity
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: mitotic recombination assay
Test system: Saccharomyces cerevisiae
Metabolic activation: with and without metabolic activation
Result: negative
Remarks: (ECHA)
Test Type: gene mutation test
Test system: S. pombe
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 480
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Metabolic activation: Metabolic activation
Method: OECD Test Guideline 473
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 479
Result: positive
Test Type: In vivo micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Test Type: dominant lethal test
Species: Mouse
Application Route: Oral
Method: OECD Test Guideline 478
Result: negative
Test Type: in vivo assay
Species: Drosophila melanogaster
Cell type: sperm
Application Route: Oral
Method: OECD Test Guideline 477
Result: negative
This product is or contains a component that is probably not carcinogenic based on its
IARC, ACGIH, NTP, or EPA classification.
Reproductive toxicity
IARC, ACGIH, NTP, or EPA classification.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: KK0875000
Nausea, Headache, Vomiting
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After absorption:
Nausea
Vomiting
Headache
Dizziness confusion drop in blood pressure
Unconsciousness
Shortness of breath
Circulatory collapse
Absorption can result in damage to:
Liver
Kidney
Central nervous system
This substance should be handled with particular care.
Nausea, Headache, Vomiting
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After absorption:
Nausea
Vomiting
Headache
Dizziness confusion drop in blood pressure
Unconsciousness
Shortness of breath
Circulatory collapse
Absorption can result in damage to:
Liver
Kidney
Central nervous system
This substance should be handled with particular care.
12.1 Toxicity
Toxicity to fish flow-through test LC50 - Gambusia affinis (Mosquito fish) - 15.2 mg/l - 96 h
Remarks: (ECHA)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 212 mg/l - 48 h and other aquatic Remarks: (ECHA) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 5.6 mg/l - 72 h (DIN 38412)
Toxicity to bacteria EC50 - Pseudomonas putida - 9,600 mg/l - 17 h
Remarks: (IUCLID)
Toxicity to mortality LOEC - Oryzias latipes - 17.9 mg/l - 38 d fish(Chronic toxicity) Remarks: (ECOTOX Database) mortality NOEC - Oryzias latipes - 8.89 mg/l - 38 d
Remarks: (ECOTOX Database)
Remarks: (ECHA)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 212 mg/l - 48 h and other aquatic Remarks: (ECHA) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 5.6 mg/l - 72 h (DIN 38412)
Toxicity to bacteria EC50 - Pseudomonas putida - 9,600 mg/l - 17 h
Remarks: (IUCLID)
Toxicity to mortality LOEC - Oryzias latipes - 17.9 mg/l - 38 d fish(Chronic toxicity) Remarks: (ECOTOX Database) mortality NOEC - Oryzias latipes - 8.89 mg/l - 38 d
Remarks: (ECOTOX Database)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d (OECD Test Guideline 301F)
Biochemical Oxygen 547 mg/g
Demand (BOD) Remarks: (IUCLID)
Biochemical Oxygen 547 mg/g
Demand (BOD) Remarks: (IUCLID)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Additional ecological Discharge into the environment must be avoided.
information
information
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1135
IMDG: 1135
IATA-DGR: 1135
IMDG: 1135
IATA-DGR: 1135
14.2 UN proper shipping name
ADR/RID: ETHYLENE CHLOROHYDRIN
IMDG: ETHYLENE CHLOROHYDRIN
IATA-DGR: Ethylene chlorohydrin
Passenger Aircraft: Not permitted for transport
Cargo Aircraft: Not permitted for transport
IMDG: ETHYLENE CHLOROHYDRIN
IATA-DGR: Ethylene chlorohydrin
Passenger Aircraft: Not permitted for transport
Cargo Aircraft: Not permitted for transport
14.3 Transport hazard class(es)
ADR/RID: 6.1 (3)
IMDG: 6.1 (3)
IATA-DGR: 6.1 (3)
IMDG: 6.1 (3)
IATA-DGR: 6.1 (3)
14.4 Packaging group
ADR/RID: I
IMDG: I
IATA-DGR: -
IMDG: I
IATA-DGR: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.