Chemical Safety Data Sheet MSDS / SDS
Glyoxal
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Glyoxal
- CBnumber: CB1280241
- CAS: 107-22-2
- EINECS Number: 203-474-9
- Synonyms: Oxalaldehyde;GLYOXA
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
Hazard statements
H341 Suspected of causing genetic defects
H332 Harmful if inhaled
H319 Causes serious eye irritation
H317 May cause an allergic skin reaction
H315 Causes skin irritation
Substance
- Product name: Glyoxal
- Synonyms: Oxalaldehyde;GLYOXA
- CAS: 107-22-2
- EC number: 203-474-9
- MF: C2H2O2
- MW: 58.04
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Mixture with combustible ingredients.
Development of hazardous combustion gases or vapours possible in the event of fire.
Mixture with combustible ingredients.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
2
0
0
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed.
Storage class
Storage class (TRGS 510): 10: Combustible liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['Glyoxazal', '107-22-2', 'TWA', '0.1 mg/m3', 'USA. ACGIH Threshold Limit\nValues (TLV)'] | ['', 'Remarks', 'Dermal Sensitization\nNot classifiable as a human carcinogen', None, None] |
|---|---|---|
| ['', '', 'Dermal Sensitization Notation', None, None] | ['', '', 'PEL', '0.1 mg/m3', 'California permissible exposure\nlimits for chemical\ncontaminants (Title 8, Article\n107)'] |
TWA 0.1 mg/m3 USA. Workplace Environmental
Exposure Levels (WEEL)
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
protective clothing
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) Colorcolorless
- c) Odoryel. crystals or lt. yel. liq., mild odor
- d) Melting point/freezing pointNo data available
- e) Initial boiling point and boiling range104 °C
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash point104°C
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pH2-3 (20°C in H2O)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubilityat 20 °C soluble
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressure18 mm Hg ( 20 °C)
- p) Density1.265 g/cm3 at 20 °C
- Relative density1.265 g/mL at 25 °C
- q) Relative vapor density>1 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNot classified as explosive.
- t) Oxidizing propertiesnone
- Solubilitywater: soluble(lit.)
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
10.3 Conditions to avoid
no information available
10.4 Incompatible materials
Strong oxidizing agents, Strong bases
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
LC50 Inhalation - Rat - 4 h - 2.44 mg/l - dust/mist
Symptoms: Possible symptoms:, mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
LC50 Inhalation - Rat - 4 h - 2.44 mg/l - dust/mist
Symptoms: Possible symptoms:, mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Mixture may cause an allergic skin reaction.
Germ cell mutagenicity
Evidence of genetic defects.
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause respiratory irritation.
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Glyoxazal
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - male and female - 3,300 mg/kg (OECD Test Guideline 401)
Acute toxicity estimate Inhalation - Expert judgment - 4 h - 11.1 mg/l - vapor
LD50 Dermal - Rabbit - 10,000 mg/kg
Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema.
Liver:Other changes.
Kidney, Ureter, Bladder:Changes in tubules (including acute renal failure, acute tubular necrosis).
(RTECS)
Acute toxicity estimate Inhalation - Expert judgment - 4 h - 11.1 mg/l - vapor
LD50 Dermal - Rabbit - 10,000 mg/kg
Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema.
Liver:Other changes.
Kidney, Ureter, Bladder:Changes in tubules (including acute renal failure, acute tubular necrosis).
(RTECS)
Skin corrosion/irritation
Remarks: Causes skin irritation.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Serious eye damage/eye irritation
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: positive (OECD Test Guideline 406)
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Result: positive (OECD Test Guideline 406)
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Germ cell mutagenicity
Suspected of causing genetic defects.
Test Type: Ames test
Test system: S. typhimurium
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Result: Positive results were obtained in some in vitro tests.
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: positive
Method: OECD Test Guideline 486
Species: Rat - male and female - Liver cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male - Bone marrow
Result: negative
Carcinogenicity
Test Type: Ames test
Test system: S. typhimurium
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Result: Positive results were obtained in some in vitro tests.
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: positive
Method: OECD Test Guideline 486
Species: Rat - male and female - Liver cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male - Bone marrow
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Upper respiratory tract
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
12.1 Toxicity
MixtureNo data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
Components Glyoxazal
Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - 186 - 272 mg/l - 96 h (DIN 38412 part 15)
Toxicity to daphnia semi-static test EC50 - Americamysis bahia (Mysid) - 69.2 mg/l and other aquatic - 48 h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Skeletonema costatum (marine diatom) - 313.8 mg/l - 96 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 400 mg/l - 30 min (OECD Test Guideline 209)
Toxicity to flow-through test NOEC - Pimephales promelas (fathead fish(Chronic toxicity) minnow) - 112 mg/l - 34 d (OECD Test Guideline 210)
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 3.19 and other aquatic mg/l - 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity)
Toxicity to daphnia semi-static test EC50 - Americamysis bahia (Mysid) - 69.2 mg/l and other aquatic - 48 h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Skeletonema costatum (marine diatom) - 313.8 mg/l - 96 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 400 mg/l - 30 min (OECD Test Guideline 209)
Toxicity to flow-through test NOEC - Pimephales promelas (fathead fish(Chronic toxicity) minnow) - 112 mg/l - 34 d (OECD Test Guideline 210)
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 3.19 and other aquatic mg/l - 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity)
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
14.7 Incompatible materials
Strong oxidizing agents, Strong bases
Further information: Not classified as dangerous in the meaning of transport regulations.
Further information: Not classified as dangerous in the meaning of transport regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.