Chemical Safety Data Sheet MSDS / SDS
Metandienone
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Metandienone
- CBnumber: CB0502711
- CAS: 72-63-9
- EINECS Number: 200-787-2
- Synonyms: Metandrostenolone;Metandienone(17β-hydroxy-17α-methylandrosta-1,4-dien-3-one)
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P403+P235 Store in a well-ventilated place. Keep cool.
P370+P378 In case of fire: Use … for extinction.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P201 Obtain special instructions before use.
Hazard statements
H332 Harmful if inhaled
H225 Highly Flammable liquid and vapour
Substance
- Product name: Metandienone
- Synonyms: Metandrostenolone;Metandienone(17β-hydroxy-17α-methylandrosta-1,4-dien-3-one)
- CAS: 72-63-9
- EC number: 200-787-2
- MF: C20H28O2
- MW: 300.44
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage stabilityRecommended storage temperature
2 - 8 °C
Test for peroxide formation periodically and before distillation.
Storage class
Test for peroxide formation periodically and before distillation.
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parametersContains no substances with occupational exposure limit values.
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid, clear
- b) Colorcolorless
- c) Odorether-like
- d) Melting point/freezing pointMelting point/range: -69 °C
- e) Initial boiling point and boiling range85 °C at 1.013 hPa
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 19 %(V)
Lower explosion limit: 12 %(V) - h) Flash point-2 °C - closed cup
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pHca.7
- l) ViscosityViscosity, kinematic: 0.5 mm2/s at 20 °C
Viscosity, dynamic: No data available - m) Water solubilityat 20 °C soluble
- n) Partition coefficient n-octanol/waterRelationship (QSAR) modeling.
log Pow: -0.21 - The preceding data, or interpretation of data, was determined using Quantitative Structure Activity - o) Vapor pressure67 hPa at 20 °C
- p) Density0.867 g/cm3 at 20 °C
- Relative density1.0597 (rough estimate)
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNot classified as explosive.
- t) Oxidizing propertiesnone
- SolubilityAcetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
9.2 Other safety information
Relative vapor density3.11 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
No data available
10.3 Conditions to avoid
Heat, flames and sparks. Exposure to sunlight.
Warming.
Moisture.
Warming.
Moisture.
10.4 Incompatible materials
Alkali metals, Aluminum, Strong oxidizing agents, Bases, Amines, Magnesium, Strong acids and strong bases, Vinyl compounds
10.5 Hazardous decomposition products
Peroxides
In the event of fire: see section 5
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
May harm the unborn child.
May impair fertility.
Specific target organ toxicity - single exposure
May impair fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Cushing's syndrome
Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Cushing's syndrome
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components 1,2-dimethoxy-ethane
Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Cushing's syndrome
Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Cushing's syndrome
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - female - 5,370 mg/kg (OECD Test Guideline 401)
Acute toxicity estimate Inhalation - 11.1 mg/l - vapor (Expert judgment)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
LD50 Dermal - Rat - female - > 5,000 mg/kg (OECD Test Guideline 402)
Acute toxicity estimate Inhalation - 11.1 mg/l - vapor (Expert judgment)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
LD50 Dermal - Rat - female - > 5,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 24 h (OECD Test Guideline 405)
Result: No eye irritation - 24 h (OECD Test Guideline 405)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Remarks: The value is given in analogy to the following substances: 1-ethoxy-2-(2- methoxyethoxy)ethane
Result: negative (OECD Test Guideline 429)
Remarks: The value is given in analogy to the following substances: 1-ethoxy-2-(2- methoxyethoxy)ethane
Germ cell mutagenicity
Not mutagenic in Ames Test. Did not show mutagenic effects in animal experiments.
Test Type: unscheduled DNA synthesis assay
Test system: Human lymphocytes
Result: negative
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: positive
Method: OECD Test Guideline 474
Species: Mouse - male and female - Bone marrow
Result: negative
Method: OECD Test Guideline 475
Species: Chinese hamster - male and female - Bone marrow
Result: negative
Test Type: unscheduled DNA synthesis assay
Test system: Human lymphocytes
Result: negative
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: positive
Method: OECD Test Guideline 474
Species: Mouse - male and female - Bone marrow
Result: negative
Method: OECD Test Guideline 475
Species: Chinese hamster - male and female - Bone marrow
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
May damage the unborn child.
May damage fertility.
Specific target organ toxicity - single exposure
May damage fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
No aspiration toxicity classification
12.1 Toxicity
MixtureNo data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
Components 1,2-dimethoxy-ethane
Toxicity to fish static test LC50 - Danio rerio (zebra fish) - > 5,000 mg/l - 96 h (OECD Test Guideline 203)
Remarks: The value is given in analogy to the following substances: Tegdme
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 4,000 and other aquatic mg/l - 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 9,120 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 6,400 mg/l - 3 h (OECD Test Guideline 209)
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 320 mg/l and other aquatic - 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity) Remarks: The value is given in analogy to the following substances:
The value is given in analogy to the following substances:
Diethyleneglycol dimethylether
Remarks: The value is given in analogy to the following substances: Tegdme
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 4,000 and other aquatic mg/l - 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 9,120 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 6,400 mg/l - 3 h (OECD Test Guideline 209)
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 320 mg/l and other aquatic - 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity) Remarks: The value is given in analogy to the following substances:
The value is given in analogy to the following substances:
Diethyleneglycol dimethylether
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 2252
IMDG: 2252
IATA-DGR: 2252
IMDG: 2252
IATA-DGR: 2252
14.2 UN proper shipping name
ADR/RID: 1,2-DIMETHOXYETHANE (1,2-dimethoxy-ethane),SOLUTION
IMDG: 1,2-DIMETHOXYETHANE (1,2-dimethoxy-ethane),SOLUTION
IATA-DGR: 1,2-Dimethoxyethane (1,2-dimethoxy-ethane),SOLUTION
IMDG: 1,2-DIMETHOXYETHANE (1,2-dimethoxy-ethane),SOLUTION
IATA-DGR: 1,2-Dimethoxyethane (1,2-dimethoxy-ethane),SOLUTION
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
Alkali metals, Aluminum, Strong oxidizing agents, Bases, Amines, Magnesium, Strong acids and strong bases, Vinyl compounds
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222211118
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222211118
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.