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ChemicalBook >> CAS DataBase List >> BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-

BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-

$55 - $1450
Product name: BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-
CAS: 1054543-47-3
MF: C33H25F6N3O3
MW: 625.56
EINECS:604-604-1
MDL Number:MFCD19443178
Synonyms:BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-;Apoptosis Activator VII, Apoptozole;Apoptozole;6-BROMO-4-CHLOROQUINOLINE HYDROCHLORIDE (1:1);APOPTOSIS ACTIVATOR VII;4-((2-(3,5-bis(trifluoromethyl)phenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazole-1-yl)methyl)benzamide;Apoptozole，Apoptosis Activator VII;CS-2225

Price21 Properties Safety Information Description

21 prices

Selected condition：

Brand

AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Axon Medchem
Cayman Chemical
ChemScene
DC Chemicals
TRC

Package

5mg
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAK Scientific
Product number1922DC
Product descriptionApoptozole
Packaging25mg
Price$459
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA102708
Product descriptionApoptozole 98+%
Packaging5mg
Price$59
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA102708
Product descriptionApoptozole 98+%
Packaging10mg
Price$77
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA102708
Product descriptionApoptozole 98+%
Packaging50mg
Price$131
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberHCH0316515
Product description4-[[2-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4,5-BIS-(4-METHOXYPHENYL)-1H-IMIDAZOL-1-YL]METHYL]BENZAMIDE 95.00%
Packaging5MG
Price$501.61
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberC4803
Product descriptionApoptozole
Packaging5mg
Price$82
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberC4803
Product descriptionApoptozole
Packaging10mg
Price$154
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberC4803
Product descriptionApoptozole
Packaging25mg
Price$369
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberC4803
Product descriptionApoptozole
Packaging50mg
Price$654
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon2251
Product descriptionApoptozole 100%
Packaging10mg
Price$104.5
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number17675
Product descriptionApoptozole ≥98%
Packaging5mg
Price$73
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number17675
Product descriptionApoptozole ≥98%
Packaging10mg
Price$116
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number17675
Product descriptionApoptozole ≥98%
Packaging25mg
Price$270
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number17675
Product descriptionApoptozole ≥98%
Packaging50mg
Price$468
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-5990
Product descriptionApoptozole 99.97%
Packaging5mg
Price$55
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5990
Product descriptionApoptozole 99.97%
Packaging10mg
Price$95
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	1922DC	Apoptozole	25mg	$459	2021-12-16	Buy
Ambeed	A102708	Apoptozole 98+%	5mg	$59	2021-12-16	Buy
Ambeed	A102708	Apoptozole 98+%	10mg	$77	2021-12-16	Buy
Ambeed	A102708	Apoptozole 98+%	50mg	$131	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0316515	4-[[2-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4,5-BIS-(4-METHOXYPHENYL)-1H-IMIDAZOL-1-YL]METHYL]BENZAMIDE 95.00%	5MG	$501.61	2021-12-16	Buy
ApexBio Technology	C4803	Apoptozole	5mg	$82	2021-12-16	Buy
ApexBio Technology	C4803	Apoptozole	10mg	$154	2021-12-16	Buy
ApexBio Technology	C4803	Apoptozole	25mg	$369	2021-12-16	Buy
ApexBio Technology	C4803	Apoptozole	50mg	$654	2021-12-16	Buy
Axon Medchem	Axon2251	Apoptozole 100%	10mg	$104.5	2021-12-16	Buy
Cayman Chemical	17675	Apoptozole ≥98%	5mg	$73	2024-03-01	Buy
Cayman Chemical	17675	Apoptozole ≥98%	10mg	$116	2024-03-01	Buy
Cayman Chemical	17675	Apoptozole ≥98%	25mg	$270	2024-03-01	Buy
Cayman Chemical	17675	Apoptozole ≥98%	50mg	$468	2024-03-01	Buy
ChemScene	CS-5990	Apoptozole 99.97%	5mg	$55	2021-12-16	Buy
ChemScene	CS-5990	Apoptozole 99.97%	10mg	$95	2021-12-16	Buy

Next Last

Properties

Melting point :225-228°C
Boiling point :703.5±70.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :White solid
pka :15.98±0.50(Predicted)
color :White
InChIKey :ZIMMTPFXOMAJTQ-UHFFFAOYSA-N
SMILES :C(N)(=O)C1=CC=C(CN2C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=NC(C3=CC=C(OC)C=C3)=C2C2=CC=C(OC)C=C2)C=C1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Apoptozole is an inhibitor of heat shock protein 70 (Hsp70; 65% inhibition at 200 μM) that acts by blocking its ATPase activity. It does not act on Hsp40, Hsp60, or Hsp90. Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). It prevents the association of Hsp70 with apoptotic protease-activating factor 1 and triggers caspase activation in HeLa cells. Apoptozole (10 mg/kg, i.p.) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without significant loss of body weight.

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Suppliers and manufacturers

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$30.00 /2mg
Apoptozole CAS:1054543-47-3

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BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-

Properties

Safety Information

Description

Related product price

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