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ChemicalBook >> CAS DataBase List >> 1H-INDOLE-5-CARBOXAMIDE, 97%

1H-INDOLE-5-CARBOXAMIDE, 97%

1H-INDOLE-5-CARBOXAMIDE, 97% price.
  • $24 - $2148.3
  • Product name: 1H-INDOLE-5-CARBOXAMIDE, 97%
  • CAS: 1670-87-7
  • MF: C9H8N2O
  • MW: 160.17
  • EINECS:
  • MDL Number:MFCD07779486
  • Synonyms:1H-INDOLE-5-CARBOXAMIDE, 97%;SD-169;1H-Indole-5-carboxamide(9CI);5-(AMinocarbonyl)-1H-indole;5-CarbaMoylindole;p38 MAP Kinase Inhibitor VII, SD-169 ;5-(Aminocarbonyl)-1H-indole, 5-Carbamoylindole, 5-Carboxamidoindole;p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem
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  • aablocks
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Package
  • 1mg
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  • 50mg
  • 5mg
  • 10mM*1mLinDMSO(Solid+Solvent)
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  • 100.00mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solution)
  • 0.1G
  • 100mg
  • 250.00mg
  • 0.25G
  • 250mg
  • 500mg
  • 1g
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  • Manufactureraablocks
  • Product numberAA003EBR
  • Product description1H-indole-5-carboxamide 97%
  • Packaging100mg
  • Price$32
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003EBR
  • Product description1H-indole-5-carboxamide 97%
  • Packaging250mg
  • Price$38
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003EBR
  • Product description1H-indole-5-carboxamide 98%
  • Packaging1g
  • Price$118
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003EBR
  • Product description1H-indole-5-carboxamide 98%
  • Packaging5g
  • Price$429
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003EBR
  • Product description1H-indole-5-carboxamide 98%
  • Packaging10g
  • Price$818
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberM15524
  • Product descriptionIndole-5-carboxamide 95%
  • Packaging5G
  • Price$600
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberM15524
  • Product descriptionIndole-5-carboxamide 95%
  • Packaging1G
  • Price$140
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M005
  • Product descriptionSD-169 ≥95%
  • Packaging5mg
  • Price$70
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M010
  • Product descriptionSD-169 ≥95%
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M010
  • Product descriptionSD-169 ≥95%
  • Packaging10mg
  • Price$81
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M001
  • Product descriptionSD-169 ≥95%
  • Packaging1mg
  • Price$54
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M100
  • Product descriptionSD-169 ≥95%
  • Packaging100mg
  • Price$378
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M050
  • Product descriptionSD-169 ≥95%
  • Packaging50mg
  • Price$259
  • Updated2026-05-06
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  • ManufacturerAK Scientific
  • Product numberSYN1079
  • Product descriptionSD169
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA538658
  • Product description1H-indole-5-carboxamide 97%
  • Packaging1g
  • Price$194
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA538658
  • Product description1H-indole-5-carboxamide 97%
  • Packaging100mg
  • Price$46
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003EBR 1H-indole-5-carboxamide 97% 100mg $32 2026-05-28 Buy
aablocks AA003EBR 1H-indole-5-carboxamide 97% 250mg $38 2026-05-28 Buy
aablocks AA003EBR 1H-indole-5-carboxamide 98% 1g $118 2026-05-28 Buy
aablocks AA003EBR 1H-indole-5-carboxamide 98% 5g $429 2026-05-28 Buy
aablocks AA003EBR 1H-indole-5-carboxamide 98% 10g $818 2026-05-28 Buy
ACHEMBLOCK M15524 Indole-5-carboxamide 95% 5G $600 2026-05-27 Buy
ACHEMBLOCK M15524 Indole-5-carboxamide 95% 1G $140 2026-05-27 Buy
Adipogen Life Sciences SYN-1079-M005 SD-169 ≥95% 5mg $70 2026-05-06 Buy
Adipogen Life Sciences SYN-1079-M010 SD-169 ≥95% 10mg $81 2021-12-16 Buy
Adipogen Life Sciences SYN-1079-M010 SD-169 ≥95% 10mg $81 2026-05-06 Buy
Adipogen Life Sciences SYN-1079-M001 SD-169 ≥95% 1mg $54 2026-05-06 Buy
Adipogen Life Sciences SYN-1079-M100 SD-169 ≥95% 100mg $378 2026-05-06 Buy
Adipogen Life Sciences SYN-1079-M050 SD-169 ≥95% 50mg $259 2026-05-06 Buy
AK Scientific SYN1079 SD169 50mg $260 2021-12-16 Buy
Ambeed A538658 1H-indole-5-carboxamide 97% 1g $194 2021-12-16 Buy
Ambeed A538658 1H-indole-5-carboxamide 97% 100mg $46 2021-12-16 Buy

Properties

Melting point :159-163 °C
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Off-white solid
pka :16.25±0.30(Predicted)
color :Off-White to Light Purple
Water Solubility :water: 1mg/mL
DMSO: 10mg/mL InChI :1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChIKey :GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES :[nH]1c2c(cc1)cc(cc2)C(=O)N

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38α (IC50 = 3.2 nM) and p38β (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38γ MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested in vitro at 50 μM. SD 169 is orally active, significantly reducing p38 MAP kinase expression in T cells of nonobese diabetic mice when delivered in chow at 600 mg/kg. In this model, SD 169 also reduced the incidence of diabetes, lowered blood glucose, and improved glucose homeostasis. SD 169 also enhances axonal regeneration after sciatic nerve crush injury in rats, when given by gavage (30 mg/kg) before and after nerve damage.

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