L-Leucyl-L-Leucine methyl ester (hydrochloride)
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- $16 - $2342.01
- Product name: L-Leucyl-L-Leucine methyl ester (hydrochloride)
- CAS: 6491-83-4
- MF: C13H27ClN2O3
- MW: 294.81808
- EINECS:
- MDL Number:MFCD00155477
- Synonyms:L-Leucyl-L-Leucine methyl ester (hydrochloride);methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride;Leu-Leu-ome hydrochloride;L-Leucine, L-leucyl-, methyl ester, monohydrochloride;lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal;L-Leucyl-L-Leucine methyl ester hydrochloride, 10 mM in DMSO;H-Leu-leu-OMe hydrochloride;L-Leucyl-L-Leucine methyl ester
23 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- TRC
Package
- 100mg
- 250mg
- 1g
- 2.5g
- 5g
- 10g
- 25g
- 100G
- Manufactureraablocks
- Product numberAA00IBCH
- Product descriptionL-Leucine, L-leucyl-, methyl ester, monohydrochloride 97%
- Packaging100mg
- Price$16
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IBCH
- Product descriptionL-Leucine, L-leucyl-, methyl ester, monohydrochloride ≥98%
- Packaging250mg
- Price$19
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IBCH
- Product descriptionL-Leucine, L-leucyl-, methyl ester, monohydrochloride 97%
- Packaging1g
- Price$23
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IBCH
- Product descriptionL-Leucine, L-leucyl-, methyl ester, monohydrochloride 97%
- Packaging5g
- Price$52
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IBCH
- Product descriptionL-Leucine, L-leucyl-, methyl ester, monohydrochloride 97%
- Packaging25g
- Price$174
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberX173276
- Product description((S)-2-amino-4-methylpentanoyl)-L-leucine methyl ester hydrochloride 95%
- Packaging25G
- Price$310
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0116CW
- Product descriptionMethylleucylleucinatehydrochloride
- Packaging100mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFL48209
- Product descriptionLeu-Leu-OMe·HCl
- Packaging5g
- Price$211.1
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFL48209
- Product descriptionLeu-Leu-OMe·HCl
- Packaging10g
- Price$337.8
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFL48209
- Product descriptionLeu-Leu-OMe·HCl
- Packaging25g
- Price$541.25
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number16008
- Product descriptionL-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%
- Packaging1g
- Price$194
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number16008
- Product descriptionL-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%
- Packaging250mg
- Price$97
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number16008
- Product descriptionL-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95%
- Packaging100mg
- Price$43
- Updated2026-04-30
- Buy
- ManufacturerChem-Impex
- Product number04578
- Product descriptionLeu-Leu-OMe·HCl ≥96%(HPLC)
- Packaging1G
- Price$33.65
- Updated2026-05-19
- Buy
- ManufacturerChem-Impex
- Product number04578
- Product descriptionLeu-Leu-OMe·HCl ≥96%(HPLC)
- Packaging5G
- Price$133.5
- Updated2026-05-19
- Buy
- ManufacturerChem-Impex
- Product number04578
- Product descriptionLeu-Leu-OMe·HCl ≥96%(HPLC)
- Packaging25G
- Price$617.22
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00IBCH | L-Leucine, L-leucyl-, methyl ester, monohydrochloride 97% | 100mg | $16 | 2026-05-29 | Buy |
| aablocks | AA00IBCH | L-Leucine, L-leucyl-, methyl ester, monohydrochloride ≥98% | 250mg | $19 | 2026-05-29 | Buy |
| aablocks | AA00IBCH | L-Leucine, L-leucyl-, methyl ester, monohydrochloride 97% | 1g | $23 | 2026-05-29 | Buy |
| aablocks | AA00IBCH | L-Leucine, L-leucyl-, methyl ester, monohydrochloride 97% | 5g | $52 | 2026-05-29 | Buy |
| aablocks | AA00IBCH | L-Leucine, L-leucyl-, methyl ester, monohydrochloride 97% | 25g | $174 | 2026-05-29 | Buy |
| ACHEMBLOCK | X173276 | ((S)-2-amino-4-methylpentanoyl)-L-leucine methyl ester hydrochloride 95% | 25G | $310 | 2026-05-27 | Buy |
| AK Scientific | 0116CW | Methylleucylleucinatehydrochloride | 100mg | $133 | 2021-12-16 | Buy |
| Biosynth | FL48209 | Leu-Leu-OMe·HCl | 5g | $211.1 | 2026-06-04 | Buy |
| Biosynth | FL48209 | Leu-Leu-OMe·HCl | 10g | $337.8 | 2026-06-04 | Buy |
| Biosynth | FL48209 | Leu-Leu-OMe·HCl | 25g | $541.25 | 2026-06-04 | Buy |
| Cayman Chemical | 16008 | L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95% | 1g | $194 | 2026-04-30 | Buy |
| Cayman Chemical | 16008 | L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95% | 250mg | $97 | 2026-04-30 | Buy |
| Cayman Chemical | 16008 | L-Leucyl-L-Leucine methyl ester (hydrochloride) ≥95% | 100mg | $43 | 2026-04-30 | Buy |
| Chem-Impex | 04578 | Leu-Leu-OMe·HCl ≥96%(HPLC) | 1G | $33.65 | 2026-05-19 | Buy |
| Chem-Impex | 04578 | Leu-Leu-OMe·HCl ≥96%(HPLC) | 5G | $133.5 | 2026-05-19 | Buy |
| Chem-Impex | 04578 | Leu-Leu-OMe·HCl ≥96%(HPLC) | 25G | $617.22 | 2026-05-19 | Buy |
Properties
Melting point :177-181°C
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
Safety Information
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Description
L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.Suppliers and manufacturers
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Bide Pharmatech Ltd.
Shanghai GL Peptide Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Wuxi Asia Peptide Biotechnology Limited Company
Aikon International Limited
Shanghai Hongye Biotechnology Co. Ltd
Kanghua (Shanghai) New Drug Development Co., Ltd.
Shanghai Jifeng Biotechnology Co., Ltd.




