Ripasudil hydrochloride dihydrate
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- $14 - $3791
- Product name: Ripasudil hydrochloride dihydrate
- CAS: 887375-67-9
- MF: C15H21ClFN3O3S
- MW: 377.86
- EINECS:
- MDL Number:MFCD26960897
- Synonyms:K-115 HCL;Ripasudil free base;RipasudilHCl Hydrate;K115 HCl Dihydrate;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride dihydrate;K-115 (HCl H2O);Ripasudil HCl Dihydrate;K115 HCL 2H2O
75 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 2mg
- 10mM(1mLinDMSO)
- 1mg
- 10mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mM*1mLinDMSO
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging250mg
- Price$237
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 95%
- Packaging1g
- Price$829
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging100mg
- Price$128
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging50mg
- Price$83
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging25mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging5mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging2mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU13
- Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98404
- Product descriptionRipasudil 98%
- Packaging25MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98404
- Product descriptionRipasudil 98%
- Packaging25MG
- Price$100
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98404
- Product descriptionRipasudil 98%
- Packaging100MG
- Price$190
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98404
- Product descriptionRipasudil 98%
- Packaging100MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3757AH
- Product descriptionK-115
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging25mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging10mg
- Price$186
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 250mg | $237 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 95% | 1g | $829 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 100mg | $128 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 50mg | $83 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 25mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 5mg | $21 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 2mg | $17 | 2026-05-28 | Buy |
| aablocks | AA00GU13 | Ripasudil (K-115) hydrochloride dihydrate 98% | 1mg | $14 | 2026-05-28 | Buy |
| ACHEMBLOCK | T98404 | Ripasudil 98% | 25MG | $100 | 2026-05-27 | Buy |
| ACHEMBLOCK | T98404 | Ripasudil 98% | 25MG | $100 | 2026-05-25 | Buy |
| ACHEMBLOCK | T98404 | Ripasudil 98% | 100MG | $190 | 2026-05-25 | Buy |
| ACHEMBLOCK | T98404 | Ripasudil 98% | 100MG | $190 | 2026-05-27 | Buy |
| AK Scientific | 3757AH | K-115 | 5mg | $200 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 25mg | $242 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 10mg | $186 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
form :solid
color :White to off-white
Stability :Hygroscopic
solubility :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
form :solid
color :White to off-white
Stability :Hygroscopic
Safety Information
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Description
Ripasudil hydrochloride hydrate (Glanatec®) was approved in Japan in 2014 for the treatment of glaucoma and ocular hypertension. Originally discovered by D. Western Therapeutics Institute, Inc. and licensed by the Kowa Company, Ltd, ripasudil functions as a selective Rho-kinase inhibitor and reduces intraocular pressure by stimulation of aqueous humour drainage of the trabecular meshwork. While this recent approval allows for use of ripasudil as a twice-daily monotherapy treatment when other drugs cannot be used or are not effective, clinical trials using ripasudil as a combination therapy with other glaucoma drugs have shown promising results in the treatment of primary open-angle glaucoma or ocular hypertension. Currently, the Kowa Company is also pursuing trials focused on the use of ripasudil for the treatment of diabetic retinopathy and diabetic macular edema.More related product prices
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