AC-DEVD-CHO
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- $36 - $2193
- Product name: AC-DEVD-CHO
- CAS: 184179-08-6
- MF: C20H30N4O11
- MW: 502.47
- EINECS:
- MDL Number:MFCD00671412
- Synonyms:DEVD-CHO;CPP32/APOPAIN INHIBITOR;CPP32/APOPAIN INHIBITOR, CELL-PERMEABLE;CASPASE 3 (APOPAIN) INHIBITOR 1;CASPASE-3 INHIBITOR I;CASPASE-3 INHIBITOR I, CELL-PERMEABLE;CASPASE-3 INHIBITOR;CASPASE-3 INHIBITOR (ALDEHYDE)
14 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- Sigma-Aldrich
Package
- 500μg
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 1 unit
- ManufacturerAK Scientific
- Product number1594AH
- Product descriptionAC-DEVD-CHO
- Packaging50mg
- Price$2193
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000179
- Product descriptionCELL-PERMEABLE DEVD-CHO 95.00%
- Packaging5MG
- Price$503.72
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA108687
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
- Packaging2mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA108687
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
- Packaging5mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA108687
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
- Packaging10mg
- Price$457
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA108687
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
- Packaging25mg
- Price$913
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA108687
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
- Packaging50mg
- Price$1588
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10017
- Product descriptionAc-DEVD-CHO ≥95%
- Packaging500μg
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10017
- Product descriptionAc-DEVD-CHO ≥95%
- Packaging1mg
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10017
- Product descriptionAc-DEVD-CHO ≥95%
- Packaging5mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10017
- Product descriptionAc-DEVD-CHO ≥95%
- Packaging10mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number07655
- Product descriptionAc-Asp-Glu-Val-Asp-aldehyde(pseudoacid)
- Packaging25MG
- Price$820.02
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number235423-M
- Product descriptionCaspase-3 Inhibitor I, Cell-Permeable The Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
- Packaging1 unit
- Price$244
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product number235427
- Product descriptionCaspase-3 Inhibitor I, Cell-Permeable InSolution, ≥90%
- Packaging1mg
- Price$252
- Updated2025-07-31
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1594AH | AC-DEVD-CHO | 50mg | $2193 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000179 | CELL-PERMEABLE DEVD-CHO 95.00% | 5MG | $503.72 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA108687 | Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) | 2mg | $132 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA108687 | Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) | 5mg | $263 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA108687 | Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) | 10mg | $457 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA108687 | Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) | 25mg | $913 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA108687 | Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) | 50mg | $1588 | 2021-12-16 | Buy |
| Cayman Chemical | 10017 | Ac-DEVD-CHO ≥95% | 500μg | $36 | 2021-12-16 | Buy |
| Cayman Chemical | 10017 | Ac-DEVD-CHO ≥95% | 1mg | $61 | 2021-12-16 | Buy |
| Cayman Chemical | 10017 | Ac-DEVD-CHO ≥95% | 5mg | $230 | 2021-12-16 | Buy |
| Cayman Chemical | 10017 | Ac-DEVD-CHO ≥95% | 10mg | $425 | 2021-12-16 | Buy |
| Chem-Impex | 07655 | Ac-Asp-Glu-Val-Asp-aldehyde(pseudoacid) | 25MG | $820.02 | 2021-12-16 | Buy |
| Sigma-Aldrich | 235423-M | Caspase-3 Inhibitor I, Cell-Permeable The Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications. | 1 unit | $244 | 2025-07-31 | Buy |
| Sigma-Aldrich | 235427 | Caspase-3 Inhibitor I, Cell-Permeable InSolution, ≥90% | 1mg | $252 | 2025-07-31 | Buy |
Properties
Boiling point :1021.1±65.0 °C(Predicted)
Density :1.374±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :H2O: 1 mg/mL
form :powder
pka :4.19±0.10(Predicted)
color :white
InChIKey :UMBVAPCONCILTL-JQTTWLCSNA-N
SMILES :[C@@H](CCC(=O)O)(NC(=O)[C@@H](NC(=O)C)CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C=O)CC(=O)O |&1:0,9,21,28,r|
Density :1.374±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :H2O: 1 mg/mL
form :powder
pka :4.19±0.10(Predicted)
color :white
InChIKey :UMBVAPCONCILTL-JQTTWLCSNA-N
SMILES :[C@@H](CCC(=O)O)(NC(=O)[C@@H](NC(=O)C)CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C=O)CC(=O)O |&1:0,9,21,28,r|
Safety Information
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Description
Ac-DEVD-CHO is a potent inhibitor of the Group II caspases, caspase-3 and caspase-7 (Kis = 0.23 and 1.6 nM, respectively). Notably, it also inhibits other caspases (Kis = 18, 1710, 132, 205, 31, 0.92, 60, and 12 nM for caspases-1, -2, -4, -5, -6, -8, -9, and -10, respectively). Caspase inhibitors in the aldehyde form, like this compound, are typically reversible, whereas methyl ketone forms, like Ac-DEVD-CMK , are irreversible. Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications.Related product price
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