MG-115
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- $21 - $2221.5
- Product name: MG-115
- CAS: 133407-86-0
- MF: C25H39N3O5
- MW: 461.6
- EINECS:
- MDL Number:MFCD00274411
- Synonyms:PROTEASOME INHIBITOR MG-115;N-CBZ-LEU-LEU-NORVALINAL;MG-115;Z-LL-NVA-CHO;Z-LEU-LEU-NVA-ALDEHYDE;Z-LEU-LEU-NVA-CHO;Z-LEU-LEU-NVA-H;Z-LEU-LEU-NVA-H (ALDEHYDE)
34 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 2.5mg
- EvaluationSample
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01E12Y
- Product descriptionBenzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95%
- Packaging1mg
- Price$21
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E12Y
- Product descriptionBenzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95%
- Packaging5mg
- Price$57
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E12Y
- Product descriptionBenzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95%
- Packaging10mg
- Price$95
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E12Y
- Product descriptionBenzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95%
- Packaging25mg
- Price$190
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E12Y
- Product descriptionBenzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95%
- Packaging50mg
- Price$322
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203263
- Product descriptionMG-115 98.00%
- Packaging100MG
- Price$825
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203263
- Product descriptionMG-115 98.00%
- Packaging25MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CP3-0015-M005
- Product descriptionZ-Leu-Leu-Nva-CHO [MG-115] ≥95%(HPLC)
- Packaging5mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CP3-0015-M001
- Product descriptionZ-Leu-Leu-Nva-CHO [MG-115] ≥95%(HPLC)
- Packaging1mg
- Price$25
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2612
- Product descriptionMG-115
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2612
- Product descriptionMG-115
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2612
- Product descriptionMG-115
- Packaging25mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2612
- Product descriptionMG-115
- Packaging100mg
- Price$700
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberIFA40786
- Product descriptionMG-115
- Packaging10mg
- Price$851.7
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberIFA40786
- Product descriptionMG-115
- Packaging25mg
- Price$1388.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberIAT-3170-V
- Product descriptionZ-Leu-Leu-Nva-H (aldehyde)
- Packaging5mg
- Price$232.45
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E12Y | Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95% | 1mg | $21 | 2026-05-30 | Buy |
| aablocks | AA01E12Y | Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95% | 5mg | $57 | 2026-05-30 | Buy |
| aablocks | AA01E12Y | Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95% | 10mg | $95 | 2026-05-30 | Buy |
| aablocks | AA01E12Y | Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95% | 25mg | $190 | 2026-05-30 | Buy |
| aablocks | AA01E12Y | Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxopentan-2-yl)amino)pentan-2-yl)amino)-1-oxopentan-2-yl)carbamate 95% | 50mg | $322 | 2026-05-30 | Buy |
| ACHEMBLOCK | X203263 | MG-115 98.00% | 100MG | $825 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203263 | MG-115 98.00% | 25MG | $285 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CP3-0015-M005 | Z-Leu-Leu-Nva-CHO [MG-115] ≥95%(HPLC) | 5mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CP3-0015-M001 | Z-Leu-Leu-Nva-CHO [MG-115] ≥95%(HPLC) | 1mg | $25 | 2026-05-06 | Buy |
| ApexBio Technology | A2612 | MG-115 | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | A2612 | MG-115 | 5mg | $70 | 2026-05-06 | Buy |
| ApexBio Technology | A2612 | MG-115 | 25mg | $200 | 2026-05-06 | Buy |
| ApexBio Technology | A2612 | MG-115 | 100mg | $700 | 2026-05-06 | Buy |
| Biosynth | IFA40786 | MG-115 | 10mg | $851.7 | 2026-06-04 | Buy |
| Biosynth | IFA40786 | MG-115 | 25mg | $1388.5 | 2026-06-04 | Buy |
| Biosynth | IAT-3170-V | Z-Leu-Leu-Nva-H (aldehyde) | 5mg | $232.45 | 2026-06-04 | Buy |
Properties
Boiling point :678.8±55.0 °C(Predicted)
Density :1.082±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :11.14±0.46(Predicted)
color :white
InChIKey :WVUWUETVYUPHEM-FKBYEOEOSA-N
SMILES :C(N)(=O)[C@H](CC(C)C)N(C(=O)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O)[C@H](C=O)CCC
Density :1.082±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :11.14±0.46(Predicted)
color :white
InChIKey :WVUWUETVYUPHEM-FKBYEOEOSA-N
SMILES :C(N)(=O)[C@H](CC(C)C)N(C(=O)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O)[C@H](C=O)CCC
Safety Information
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Description
(S)-MG115 is a potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM). It reduces the degradation of ubiquitin-conjugated proteins in extracts. (S)-MG115 also blocks the degradation of long- and short-lived proteins in intact cells as well as the proteolytic generation of diverse proteins, including NF-κB, antigens, and p53. Proteasome inhibitors, including (S)-MG115, can induce a heat shock response and apoptosis, particularly in cancer cells.More related product prices
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Sigma-Aldrich
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