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ChemicalBook >> CAS DataBase List >> Charybdotoxin (trifluoroacetate salt)

Charybdotoxin (trifluoroacetate salt)

Charybdotoxin (trifluoroacetate salt) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 100μg
  • ManufacturerCayman Chemical
  • Product number24115
  • Product descriptionCharybdotoxin (trifluoroacetate salt) ≥95%
  • Packaging100μg
  • Price$294
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 24115 Charybdotoxin (trifluoroacetate salt) ≥95% 100μg $294 2026-04-30 Buy

Properties

solubility :Water: 1 mg/ml

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Charybdotoxin is a peptide originally isolated from the scorpion L. quinquestriatus that acts as a potassium channel blocker.1,2 It blocks large-conductance Ca2+-activated K+ channels (BKCas) in GH3 rat pituitary tumor cells and primary bovine aortic smooth muscle cells (Kds = 2.1 and ~2.1 nM, respectively).2 Charybdotoxin selectively blocks voltage-gated potassium (Kv) channels Kv1.2 and Kv1.3 over Kv1.1, Kv1.5, and Kv3.1 (Kds = 14, 2.6, >1,000, >100, >1,000 nM, respectively).3 It also blocks human large-conductance pH-activated potassium channel KCa5.1 (Slo3) by 47% at a concentration of 100 nM and pH of 7.4, and human intermediate-conductance Ca2+-activated K+ channel IKCa1/KCa3.1 (Kd = 10 nM).4,5WARNING This product is not for human or veterinary use.

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