EGF816
|
- $30 - $2450
- Product name: EGF816
- CAS: 1508250-71-2
- MF: C26H31ClN6O2
- MW: 495.02
- EINECS:
- MDL Number:MFCD28963918
- Synonyms:Nazartinib (EGF816);EGF816, 98%, a novel EGFR inhibitor;EGF816;NVS-816;Nazartinib (EGF816, NVS-816);(R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide;EGF816 Nazartinib;CS-1646
44 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging2mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging1mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging10mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging25mg
- Price$145
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging50mg
- Price$261
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging100mg
- Price$436
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001MSR
- Product descriptionEGF816 98%
- Packaging250mg
- Price$863
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15701
- Product descriptionEGF-816 98%
- Packaging1G
- Price$2450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15701
- Product descriptionEGF-816 98%
- Packaging100MG
- Price$495
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15701
- Product descriptionEGF-816 98%
- Packaging25MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15701
- Product descriptionEGF-816 98%
- Packaging5MG
- Price$65
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3883DW
- Product descriptionNazartinib
- Packaging25mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005714
- Product description(R,E)-N-(7-CHLORO-1-(1-(4-(DIMETHYLAMINO)BUT-2-ENOYL)AZEPAN-3-YL)-1H-BENZO[D]IMIDAZOL-2-YL)-2-METHYLISONICOTINAMIDE 95.00%
- Packaging5MG
- Price$505.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5889
- Product descriptionEGF816
- Packaging50mg
- Price$615
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5889
- Product descriptionEGF816
- Packaging25mg
- Price$359
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001MSR | EGF816 98% | 2mg | $42 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 1mg | $30 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 10mg | $87 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 25mg | $145 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 50mg | $261 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 100mg | $436 | 2026-05-28 | Buy |
| aablocks | AA001MSR | EGF816 98% | 250mg | $863 | 2026-05-28 | Buy |
| ACHEMBLOCK | M15701 | EGF-816 98% | 1G | $2450 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15701 | EGF-816 98% | 100MG | $495 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15701 | EGF-816 98% | 25MG | $195 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15701 | EGF-816 98% | 5MG | $65 | 2026-05-27 | Buy |
| AK Scientific | 3883DW | Nazartinib | 25mg | $765 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005714 | (R,E)-N-(7-CHLORO-1-(1-(4-(DIMETHYLAMINO)BUT-2-ENOYL)AZEPAN-3-YL)-1H-BENZO[D]IMIDAZOL-2-YL)-2-METHYLISONICOTINAMIDE 95.00% | 5MG | $505.45 | 2021-12-16 | Buy |
| ApexBio Technology | B5889 | EGF816 | 50mg | $615 | 2026-05-06 | Buy |
| ApexBio Technology | B5889 | EGF816 | 25mg | $359 | 2026-05-06 | Buy |
Properties
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :11.38±0.43(Predicted)
color :Off-white to yellow
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :11.38±0.43(Predicted)
color :Off-white to yellow
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Nazartinib is an irreversible inhibitor of mutant EGF receptors (EGFRs). It is selective for EGFR mutant cell lines, including H3255 and HCC827 lung adenocarcinoma cells (IC50s = 6.11 and 1.52 nM, respectively) and resistant H1975 non-small cell lung cancer cells (NSCLC; IC50 = 4.18 nM), over cells expressing wild-type EGFRs (IC50 = 160.6 nM for HaCaT keratinocytes). Nazartinib decreases phosphorylation of EGFR in H3255, HCC827, and H1975 cells (EC50s = 5, 1, and 3 nM, respectively) and inhibits cell proliferation (EC50s = 9, 11, and 25 nM, respectively) but does not affect cell proliferation in cell lines containing wild-type EGFR. It reduces tumor growth in an HCC827 lung adenocarcinoma mouse xenograft model when administered at doses ranging from 3 to 100 mg/kg per day for 21 days.More related product prices
AZD-9291 Dacomitinib (PF299804) CO-1686 Poziotinib (HM781-36B) Neratinib Irbinitinib OSI-420 AG 1478 HYDROCHLORIDE AZD 3759 Genistein Olmutinib XL-647Related product price
-
AZD-9291
$4-1800 -
Dacomitinib (PF299804)
$10-1703 -
CO-1686
$9-3510
Suppliers and manufacturers
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
TargetMol Chemicals Inc.
Zhengzhou Anbu Chem Co.,Ltd
Zibo Hangyu Biotechnology Development Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.
Henan Fengda Chemical Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
