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ChemicalBook >> CAS DataBase List >> GSK484

GSK484

GSK484 price.
  • $42 - $4095
  • Product name: GSK484
  • CAS: 1652591-81-5
  • MF: C27H32ClN5O3
  • MW: 510.04
  • EINECS:
  • MDL Number:
  • Synonyms:GSK484;GSK484 (hydrochloride);CS-2265;PAD4 inhibitor GS484;GSK484 HCl;((3S,4R)-3-amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride;AOB6992;GTPL8577
Price56 Properties Safety Information Description
56 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Synthonix
  • TRC
Package
  • 10mM(1mLinDMSO)
  • 500μg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mg
  • 10mM*1mLinDMSO
  • 25MG
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98
  • Packaging1mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98
  • Packaging5mg
  • Price$140
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98%
  • Packaging10mg
  • Price$157
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98%
  • Packaging50mg
  • Price$246
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98%
  • Packaging100mg
  • Price$418
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98%
  • Packaging250mg
  • Price$713
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ASBL
  • Product description((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98%
  • Packaging1g
  • Price$2676
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88563
  • Product descriptionGSK484 98%
  • Packaging100MG
  • Price$510
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88563
  • Product descriptionGSK484 98%
  • Packaging25MG
  • Price$180
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5686
  • Product descriptionGSK484
  • Packaging100mg
  • Price$2663
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging25mg
  • Price$718
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging5mg
  • Price$254
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$329
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$329
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging10mM(1mLinDMSO)
  • Price$283
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98 1mg $72 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98 5mg $140 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98% 10mg $157 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98% 50mg $246 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98% 100mg $418 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98% 250mg $713 2026-05-28 Buy
aablocks AA00ASBL ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride 98% 1g $2676 2026-05-28 Buy
ACHEMBLOCK S88563 GSK484 98% 100MG $510 2026-05-27 Buy
ACHEMBLOCK S88563 GSK484 98% 25MG $180 2026-05-27 Buy
AK Scientific SYN5686 GSK484 100mg $2663 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 25mg $718 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 5mg $254 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 10mg $370 2021-12-16 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 10mM*1mLinDMSO(Solid+Solvent) $329 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 10mM*1mLinDMSO(Solution) $329 2026-05-26 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 10mM(1mLinDMSO) $283 2026-05-26 Buy
Next Last

Properties

storage temp. :2-8°C
solubility :DMSO:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
Ethanol:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
PBS buffer (pH 7.2):5.0(Max Conc. mg/mL);9.8(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);58.82(Max Conc. mM) form :powder
color :white to beige
Water Solubility :H2O: 2mg/mL, clear (warmed)
InChIKey :MULKOGJHUZTANI-JEGYXLSDNA-N
SMILES :C(C1CC1)N1C2=CC=CC=C2C=C1C1=NC2=CC(C(N3CC[C@@H](O)[C@@H](N)C3)=O)=CC(OC)=C2N1C.Cl |&1:22,24,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GSK484 is a reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils. It exhibits favorable pharmacokinetic profiles in mouse and rat. See the Structural Genomics Consortium (SGC) website for more information.

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6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide GSK481 GSK461364 GSK583 1346572-63-1 RET Kinase inhibitor 1 864082-47-3 GSK2636771 GSK2982772 GSK 2334470 GSK J4 HCl GSK864 1346574-57-9 188591-46-0 GSK2837808A GSK-2256098 942206-85-1 GSK6853 GSK 2033

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Suppliers and manufacturers

TargetMol Chemicals Inc.
GSK484 hydrochloride
$65.00
GSK484 hydrochloride CAS:1652591-81-5
Career Henan Chemica Co
Zhejiang J&C Biological Technology Co.,Limited
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Amadis Chemical Company Limited Changzhou Borl Biotechnology Co.,LTD Hubei Chuchang Chemical Co., Ltd Beijing Ouhe Technology Co., Ltd