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ChemicalBook >> CAS DataBase List >> GW441756

GW441756

GW441756 price.
  • $12 - $2841
  • Product name: GW441756
  • CAS: 504433-23-2
  • MF: C17H13N3O
  • MW: 275.3
  • EINECS:
  • MDL Number:MFCD08703104
  • Synonyms:1,3-DIHYDRO-3-[(1-METHYL-1H-INDOL-3-YL)METHYLENE]-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE;GW 441756;2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-;(Z)-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one;3-[(1-METHYLINDOL-3-YL)METHYLIDENE]-1H-PYRROLO[3,2-B]PYRIDIN-2-ONE;HYDROCHLORIDE;GW 441756; GW-441756
58 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Tocris
  • TRC
Package
  • 250mg
  • 500mg
  • 1000mg
  • 50.00g
  • 100.00g
  • 10mM(1mLinDMSO)
  • 50
  • 10
  • 250.00g
  • 1mg
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • 1G
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA006Z5M
  • Product descriptionGW441756 98%
  • Packaging1mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006Z5M
  • Product descriptionGW441756 98%
  • Packaging5mg
  • Price$22
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA006Z5M
  • Product descriptionGW441756 98%
  • Packaging10mg
  • Price$31
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberO33829
  • Product descriptionGW441756 98%
  • Packaging5MG
  • Price$30
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberO33829
  • Product descriptionGW441756 98%
  • Packaging25MG
  • Price$75
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberO33829
  • Product descriptionGW441756 98%
  • Packaging100MG
  • Price$235
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33829
  • Product descriptionGW441756 98%
  • Packaging1G
  • Price$935
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M050
  • Product descriptionGW-441756 ≥95%
  • Packaging50mg
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M050
  • Product descriptionGW-441756 ≥95%
  • Packaging50mg
  • Price$491
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M010
  • Product descriptionGW-441756 ≥95%
  • Packaging10mg
  • Price$124
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M005
  • Product descriptionGW-441756 ≥95%
  • Packaging5mg
  • Price$108
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M001
  • Product descriptionGW-441756 ≥95%
  • Packaging1mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1044-M001
  • Product descriptionGW-441756 ≥95%
  • Packaging1mg
  • Price$65
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1044
  • Product descriptionGW441756
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number2452AH
  • Product descriptionGW441756
  • Packaging25mg
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2452AH
  • Product descriptionGW441756
  • Packaging100mg
  • Price$363
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA006Z5M GW441756 98% 1mg $12 2026-05-28 Buy
aablocks AA006Z5M GW441756 98% 5mg $22 2026-05-28 Buy
aablocks AA006Z5M GW441756 98% 10mg $31 2026-05-28 Buy
ACHEMBLOCK O33829 GW441756 98% 5MG $30 2026-05-27 Buy
ACHEMBLOCK O33829 GW441756 98% 25MG $75 2026-05-27 Buy
ACHEMBLOCK O33829 GW441756 98% 100MG $235 2026-05-27 Buy
ACHEMBLOCK O33829 GW441756 98% 1G $935 2026-05-27 Buy
Adipogen Life Sciences SYN-1044-M050 GW-441756 ≥95% 50mg $491 2021-12-16 Buy
Adipogen Life Sciences SYN-1044-M050 GW-441756 ≥95% 50mg $491 2026-05-06 Buy
Adipogen Life Sciences SYN-1044-M010 GW-441756 ≥95% 10mg $124 2026-05-06 Buy
Adipogen Life Sciences SYN-1044-M005 GW-441756 ≥95% 5mg $108 2026-05-06 Buy
Adipogen Life Sciences SYN-1044-M001 GW-441756 ≥95% 1mg $65 2021-12-16 Buy
Adipogen Life Sciences SYN-1044-M001 GW-441756 ≥95% 1mg $65 2026-05-06 Buy
AK Scientific SYN1044 GW441756 5mg $120 2021-12-16 Buy
AK Scientific 2452AH GW441756 25mg $184 2021-12-16 Buy
AK Scientific 2452AH GW441756 100mg $363 2021-12-16 Buy

Properties

Boiling point :568.0±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 5 mg/ml).
pka :11.04±0.20(Predicted)
form :solid
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The high affinity nerve growth factor (NGF) receptor, also known as NGF tyrosine kinase receptor A (TrkA), is involved in the development and maturation of the nervous system. Aberrant expression is associated with certain forms of cancer and congenital insensitivity to pain with anhidrosis. GW 441756 is a potent inhibitor of TrkA (IC50 = 2 nM). It displays >100-fold selectivity over a panel of related kinases. GW 441756 has been used to clarify the role of TrkA in regulating gene expression in neuroblastoma cells and, more recently, in amyloid-β protein precursor cleavage in neuroglioma cells.

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