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ChemicalBook >> CAS DataBase List >> L-AP4

L-AP4

L-AP4 price.
  • $76 - $1590.4
  • Product name: L-AP4
  • CAS: 23052-81-5
  • MF: C4H10NO5P
  • MW: 183.1
  • EINECS:200-258-5
  • MDL Number:MFCD00083244
  • Synonyms:L-AP4;L(+)-2-AMINO-4-PHOSPHONOBUTANOIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4);L(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID 97%;(2S)-2-Amino-4-phosphonobutyric acid;(S)-4-Phosphono-2-aminobutanoic acid;(S)-4-Phosphono-2-aminobutyric acid
Price41 Properties Safety Information Description
41 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10μg
  • 50μG
  • 1mg
  • 0.5mg
  • 50
  • 10
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 50 μg
  • Manufactureraablocks
  • Product numberAA00I4FT
  • Product descriptionL-AP4 ≥95%
  • Packaging1mg
  • Price$76
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I4FT
  • Product descriptionL-AP4 ≥95%
  • Packaging5mg
  • Price$209
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I4FT
  • Product descriptionL-AP4 ≥95%
  • Packaging10mg
  • Price$267
  • Updated2026-05-29
  • Buy
  • ManufacturerAK Scientific
  • Product number3480AL
  • Product descriptionL-Ap4
  • Packaging50mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3480AL
  • Product descriptionL-Ap4
  • Packaging10mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6202
  • Product descriptionL-AP4
  • Packaging10mg
  • Price$402
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6202
  • Product descriptionL-AP4
  • Packaging50mg
  • Price$1462
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb530414
  • Product descriptionGDF5
  • Packaging10μg
  • Price$822.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging5mg
  • Price$1073.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging10mg
  • Price$1590.4
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging2mg
  • Price$579.72
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging1mg
  • Price$391.3
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFA01291
  • Product descriptionL-AP4
  • Packaging0.5mg
  • Price$264.13
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number14538
  • Product descriptionL-AP4 ≥95%
  • Packaging10mg
  • Price$267
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number14538
  • Product descriptionL-AP4 ≥95%
  • Packaging1mg
  • Price$76
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I4FT L-AP4 ≥95% 1mg $76 2026-05-29 Buy
aablocks AA00I4FT L-AP4 ≥95% 5mg $209 2026-05-29 Buy
aablocks AA00I4FT L-AP4 ≥95% 10mg $267 2026-05-29 Buy
AK Scientific 3480AL L-Ap4 50mg $640 2021-12-16 Buy
AK Scientific 3480AL L-Ap4 10mg $218 2021-12-16 Buy
ApexBio Technology B6202 L-AP4 10mg $402 2026-05-06 Buy
ApexBio Technology B6202 L-AP4 50mg $1462 2026-05-06 Buy
Biorbyt Ltd orb530414 GDF5 10μg $822.8 2021-12-16 Buy
Biosynth FA01291 L-AP4 5mg $1073.5 2026-06-04 Buy
Biosynth FA01291 L-AP4 10mg $1590.4 2026-06-04 Buy
Biosynth FA01291 L-AP4 50mg $437.5 2021-12-16 Buy
Biosynth FA01291 L-AP4 2mg $579.72 2026-06-04 Buy
Biosynth FA01291 L-AP4 1mg $391.3 2026-06-04 Buy
Biosynth FA01291 L-AP4 0.5mg $264.13 2026-06-04 Buy
Cayman Chemical 14538 L-AP4 ≥95% 10mg $267 2026-04-30 Buy
Cayman Chemical 14538 L-AP4 ≥95% 1mg $76 2026-04-30 Buy
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Properties

Melting point :207-215 °C
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
biological source :human
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
InChI :1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChIKey :DDOQBQRIEWHWBT-VKHMYHEASA-N
SMILES :N[C@@H](CCP(O)(O)=O)C(O)=O
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Metabotropic glutamate receptors (mGluR) function to modulate excitatory synaptic transmission in the brain. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7, and 8) inhibit adenylyl cyclase. L-AP4, an analog of L-glutamic acid, is a selective Group III mGluR agonist that functions presynaptically to suppress glutamate release (IC50 = 2.5 μM). L-AP4 has been shown to depress synaptic transmission in glutamatergic pathways in the hippocampus, olfactory bulb, and retina as well as act as an agonist at the quisqualate-sensitized AP6 site in hippocampus.

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(S)-2-Amino-2-methyl-4-phosphonobutanoic acid 20263-07-4 1,2-Diaminopropane L-AP4

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. Wuhan Chemwish Technology Co., Ltd Ascent Scientific Shanghai Sinch Parmaceuticals Tech. Co. Ltd. Spectrum Chemical Manufacturing Corp. BOC Sciences Shanghai Balmxy Pharmaceutical Co., Ltd Sigma-Aldrich Shanghai Lollane Biological Technology Co.,Ltd.