L-THREO-SPHINGOSINE
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- $141 - $2587
- Product name: L-THREO-SPHINGOSINE
- CAS: 25695-95-8
- MF: C18H37NO2
- MW: 299.49
- EINECS:
- MDL Number:MFCD02259136
- Synonyms:(2S,3S,4E)-2-AMINO-1,3-OCTADEC-4-ENEDIOL;(2S,3S,4E)-2-AMINOOCTADEC-4-ENE-1,3-DIOL;L-THREO-SPHINGOSINE;L-THREO-SPHINGOSINE, C18 CHAIN;(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol;L-threo-C18-Sphingosine;threo-(2S,3S)-Sphingosine;L-THREO-SPHINGOSINE C-18
16 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA00BCWM
- Product description(2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98%
- Packaging5mg
- Price$141
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BCWM
- Product description(2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98%
- Packaging10mg
- Price$268
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BCWM
- Product description(2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98%
- Packaging25mg
- Price$564
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BCWM
- Product description(2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98%
- Packaging50mg
- Price$986
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number1366AH
- Product description2S-Amino-4E-octadecene-1,3S-diol
- Packaging100mg
- Price$1990
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4717
- Product descriptionL-threo-Sphingosine C-18
- Packaging100mg
- Price$2587
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4717
- Product descriptionL-threo-Sphingosine C-18
- Packaging50mg
- Price$1478
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4717
- Product descriptionL-threo-Sphingosine C-18
- Packaging10mg
- Price$351
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4717
- Product descriptionL-threo-Sphingosine C-18
- Packaging5mg
- Price$185
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-117152
- Product descriptionL-threo-Sphingosine
- Packaging5mg
- Price$360
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) ≥98%
- Packaging25mg
- Price$564
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) ≥98%
- Packaging50mg
- Price$986
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) ≥98%
- Packaging10mg
- Price$268
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) >98%
- Packaging100mg
- Price$1698
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) ≥98%
- Packaging5mg
- Price$141
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0064009
- Product descriptionL-threo-Sphingosine 98%
- Packaging5mg
- Price$310
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BCWM | (2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98% | 5mg | $141 | 2026-05-28 | Buy |
| aablocks | AA00BCWM | (2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98% | 10mg | $268 | 2026-05-28 | Buy |
| aablocks | AA00BCWM | (2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98% | 25mg | $564 | 2026-05-28 | Buy |
| aablocks | AA00BCWM | (2S,3S,E)-2-Aminooctadec-4-ene-1,3-diol ≥98% | 50mg | $986 | 2026-05-28 | Buy |
| AK Scientific | 1366AH | 2S-Amino-4E-octadecene-1,3S-diol | 100mg | $1990 | 2021-12-16 | Buy |
| ApexBio Technology | C4717 | L-threo-Sphingosine C-18 | 100mg | $2587 | 2026-05-06 | Buy |
| ApexBio Technology | C4717 | L-threo-Sphingosine C-18 | 50mg | $1478 | 2026-05-06 | Buy |
| ApexBio Technology | C4717 | L-threo-Sphingosine C-18 | 10mg | $351 | 2026-05-06 | Buy |
| ApexBio Technology | C4717 | L-threo-Sphingosine C-18 | 5mg | $185 | 2026-05-06 | Buy |
| Arctom | HY-117152 | L-threo-Sphingosine | 5mg | $360 | 2026-05-26 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) ≥98% | 25mg | $564 | 2026-04-30 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) ≥98% | 50mg | $986 | 2026-04-30 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) ≥98% | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) >98% | 100mg | $1698 | 2024-03-01 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) ≥98% | 5mg | $141 | 2026-04-30 | Buy |
| ChemScene | CS-0064009 | L-threo-Sphingosine 98% | 5mg | $310 | 2026-06-04 | Buy |
Properties
Melting point :86-88 °C
Boiling point :445.9±45.0 °C(Predicted)
Density :0.939±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :11.80±0.45(Predicted)
InChI :1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18-/m0/s1
InChIKey :WWUZIQQURGPMPG-DNWQSSKHSA-N
SMILES :CCCCCCCCCCCCC/C=C/[C@@](O)([H])[C@@]([H])(N)CO
Boiling point :445.9±45.0 °C(Predicted)
Density :0.939±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :11.80±0.45(Predicted)
InChI :1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18-/m0/s1
InChIKey :WWUZIQQURGPMPG-DNWQSSKHSA-N
SMILES :CCCCCCCCCCCCC/C=C/[C@@](O)([H])[C@@]([H])(N)CO
Safety Information
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Description
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits PKC (protein kinase C) in mixed micelle assays with 50% inhibition at 2.2 mol % making it a slightly more stronger inhibitor compared to D-erythro-sphingosine (50% inhibition at 2.8 mol %) or other analogs of shorter alkyl chain length. Addition of L-threo-Sphingosine C-18 to primary cultured cerebellar cells does not decrease serine palmitoyltransferase (SPT) activity, the rate-limiting enzyme in ceramide biosynthesis, whereas under similar conditions D-erythro-sphingosine inhibits SPT activity. Sphingosines are long-chain base precursors of cellular sphingolipids and are used directly in the synthesis of ceramide. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally.More related product prices
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