Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> MK8245

MK8245

MK8245 price.
  • $32 - $2244
  • Product name: MK8245
  • CAS: 1030612-90-8
  • MF: C17H16BrFN6O4
  • MW: 467.25
  • EINECS:
  • MDL Number:MFCD20039622
  • Synonyms:MK 8245;MK8245;5-[3-[4-(2-Bromo-5-fluorophenoxy)-1-piperidinyl]-5-isoxazolyl]-2H-tetrazole-2-acetic acid;2-(5-(3-(4-(2-broMo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid;MK8245;MK-8245;MK 8245;CS-1662;]-2H-tetrazoL;]-5-isoxazoL;5-[3-[4-(2-Bromo-5-fL
Price54 Properties Safety Information Description
54 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 10mM(1mLinDMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mM(in1mLDMSO)
  • 10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging1mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging2mg
  • Price$38
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging5mg
  • Price$70
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging10mg
  • Price$111
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging50mg
  • Price$193
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging25mg
  • Price$161
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 99%
  • Packaging100mg
  • Price$385
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 98%
  • Packaging250mg
  • Price$815
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TFH
  • Product descriptionMK-8245 98%
  • Packaging1g
  • Price$2244
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15370
  • Product descriptionMK-8245 98%
  • Packaging1G
  • Price$850
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15370
  • Product descriptionMK-8245 98%
  • Packaging100MG
  • Price$275
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15370
  • Product descriptionMK-8245 98%
  • Packaging25MG
  • Price$95
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15370
  • Product descriptionMK-8245 98%
  • Packaging5MG
  • Price$35
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0300
  • Product descriptionMK-8245
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA515360
  • Product descriptionMk-8245 98%
  • Packaging50mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA515360
  • Product descriptionMk-8245 98%
  • Packaging25mg
  • Price$241
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008TFH MK-8245 99% 1mg $32 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 2mg $38 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 5mg $70 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 10mg $111 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 50mg $193 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 25mg $161 2026-05-28 Buy
aablocks AA008TFH MK-8245 99% 100mg $385 2026-05-28 Buy
aablocks AA008TFH MK-8245 98% 250mg $815 2026-05-28 Buy
aablocks AA008TFH MK-8245 98% 1g $2244 2026-05-28 Buy
ACHEMBLOCK M15370 MK-8245 98% 1G $850 2026-05-27 Buy
ACHEMBLOCK M15370 MK-8245 98% 100MG $275 2026-05-27 Buy
ACHEMBLOCK M15370 MK-8245 98% 25MG $95 2026-05-27 Buy
ACHEMBLOCK M15370 MK-8245 98% 5MG $35 2026-05-27 Buy
AK Scientific Y0300 MK-8245 10mg $288 2021-12-16 Buy
Ambeed A515360 Mk-8245 98% 50mg $313 2021-12-16 Buy
Ambeed A515360 Mk-8245 98% 25mg $241 2021-12-16 Buy
Next Last

Properties

Boiling point :698.3±65.0 °C(Predicted)
Density :1.82
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥23.35 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :2.85±0.10(Predicted)
color :White to off-white
InChI :1S/C17H16BrFN6O4/c18-12-2-1-10(19)7-13(12)28-11-3-5-24(6-4-11)15-8-14(29-22-15)17-20-23-25(21-17)9-16(26)27/h1-2,7-8,11H,3-6,9H2,(H,26,27)
InChIKey :UJEAABFSXKCSGI-UHFFFAOYSA-N
SMILES :Fc1cc(c(cc1)Br)OC2CCN(CC2)c3n[o]c(c3)c4n[n](nn4)CC(=O)O

Safety Information

Symbol(GHS): Flame (GHS02)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H242 Heating may cause a fire Self-reactive substances and mixtures; and Organic peroxides Type C, D,Type E, F
Type G		 Danger
Warning		 P210, P220, P234, P280, P370+P378,P403+P235, P411, P420, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234 Keep only in original container.
P235 Keep cool.
P240 Ground/bond container and receiving equipment.
P370+P378 In case of fire: Use … for extinction.
P403 Store in a well-ventilated place.

Description

MK-8245 is a liver-targeted inhibitor of stearoyl-CoA desaturase (SCD; IC50s = 3, 3, and 1 nM for rat, mouse, and human SCD1, respectively). It is selective for SCD1 over Δ5- and Δ6-desaturases (IC50s = >100,000 nM). MK-8245 (20-60 mg/kg) reduces the hepatic, but not Harderian gland, ratio of oleic acid to stearic acid, a marker of chronic SCD activity, and blood glucose levels, without inducing the formation of skin lesions or eye squinting behavior, in a mouse model of high-fat diet-induced obesity. It also inhibits hepatitis C virus (HCV) replication without inducing cytotoxicity in LucNeo2 cells (IC50 = 39.8 nM).

More related product prices

Canertinib Olaparib MG-132 ABT-199 Conivaptan hydrochloride PI-103

Related product price

Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. BOC Sciences Dalian Meilun Biotech Co., Ltd. NCE Biomedical Co.,Ltd. Haoyuan Chemexpress Co., Ltd. Shanghai Aladdin Bio-Chem Technology Co.,LTD Nanjing Dulai Biotechnology Co., Ltd. AdooQ BioScience, LLC ApexBio Technology LLC Bide Pharmatech Ltd.