Olaparib
|
- $11 - $2994.75
- Product name: Olaparib
- CAS: 763113-22-0
- MF: C24H23FN4O3
- MW: 434.46
- EINECS:642-941-5
- MDL Number:MFCD13185161
- Synonyms:Olaparid AZD2281;KU 59436;AZD2281(olaparib)/AZD-2281;AZD2281(olaparib);4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;Olaparib, 99%, PARP inhibitor;AZD 2281 - Olaparib | KU 0059436;AZD2281; KU-0059436; KU0059436; AZD-2281; KU0059436; AZD 2281
95 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TCI Chemical
- TRC
- Usbiological
Package
- 1unit
- 10mM(in 1mL DMSO)
- EvaluationSample
- 5mg
- 10mM*1mLinDMSO
- 1mg
- 20mg
- 2x25mg
- 200mg
- 2g
- 10mM(in1mLDMSO)
- 10MG
- 25mg
- 50MG
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98%
- Packaging25mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98%
- Packaging100mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98%
- Packaging250mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98%
- Packaging1g
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine 98%
- Packaging5g
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine 98%
- Packaging10g
- Price$81
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036H5
- Product description1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98%
- Packaging25g
- Price$180
- Updated2026-05-28
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99.00%
- Packaging5G
- Price$230
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging10G
- Price$1050
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging25G
- Price$1910
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99.00%
- Packaging1G
- Price$130
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product numberF-4545
- Product descriptionOlaparib 98%
- Packaging25G
- Price$192
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberF-4545
- Product descriptionOlaparib 98%
- Packaging5G
- Price$60
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberF-4545
- Product descriptionOlaparib 98%
- Packaging1G
- Price$16
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-O0144-M100
- Product descriptionOlaparib ≥98%(HPLC)
- Packaging100mg
- Price$105
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-O0144-G001
- Product descriptionOlaparib ≥98%(HPLC)
- Packaging1g
- Price$460
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98% | 25mg | $11 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98% | 100mg | $12 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98% | 250mg | $14 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98% | 1g | $19 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine 98% | 5g | $50 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine 98% | 10g | $81 | 2026-05-28 | Buy |
| aablocks | AA0036H5 | 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine ≥98% | 25g | $180 | 2026-05-28 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99.00% | 5G | $230 | 2026-05-21 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 10G | $1050 | 2026-05-21 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 25G | $1910 | 2026-05-21 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99.00% | 1G | $130 | 2026-05-21 | Buy |
| ACHEMBLOCK | F-4545 | Olaparib 98% | 25G | $192 | 2026-05-27 | Buy |
| ACHEMBLOCK | F-4545 | Olaparib 98% | 5G | $60 | 2026-05-27 | Buy |
| ACHEMBLOCK | F-4545 | Olaparib 98% | 1G | $16 | 2026-05-27 | Buy |
| Adipogen Life Sciences | CDX-O0144-M100 | Olaparib ≥98%(HPLC) | 100mg | $105 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-O0144-G001 | Olaparib ≥98%(HPLC) | 1g | $460 | 2026-05-06 | Buy |
Properties
Density :1.43
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13-14,16,26H,6-7,9-12H2,(H,27,30)
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13-14,16,26H,6-7,9-12H2,(H,27,30)
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
Safety Information
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| Signal word: | Danger | ||||||||||||||||||
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Description
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.More related product prices
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Suppliers and manufacturers
Shanghai Jinyin Biological Technology Co., Ltd
Shandong Platinum Pharmaceutical Co., Ltd.
Hubei widely chemical technology Co., Ltd.
Jinan Yuantai Pharmaceutical Co.,Ltd
Hainan Chenghe Pharmaceutical Technology Co., Ltd
Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
Hangzhou Read Chemical Co., Ltd
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.