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ChemicalBook >> CAS DataBase List >> MS436

MS436

$67 - $1181
Product name: MS436
CAS: 1395084-25-9
MF: C18H17N5O3S
MW: 383.42
EINECS:
MDL Number:MFCD27992062
Synonyms:(E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide;MS-436; MS 436;4-[(2Z)-2-(2-amino-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-N-pyridin-2-ylbenzenesulfonamide;CS-1882;MS436(95%);4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide;4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide MS436;MS436 4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide

Price19 Properties Safety Information Description

19 prices

Selected condition：

Brand

AK Scientific
Ambeed
ApexBio Technology
BroadPharm
ChemScene
Crysdot
DC Chemicals
Tocris
TRC

Package

10mg
50
5mg
25mg
50mg
100mg
250mg
10
1g

ManufacturerAK Scientific
Product numberY1865
Product descriptionMS436
Packaging10mg
Price$218.75
Updated2021-12-16
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ManufacturerAK Scientific
Product numberY1865
Product descriptionMS436
Packaging100mg
Price$927.5
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113750
Product descriptionMS436 98+%
Packaging5mg
Price$67
Updated2021-12-16
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ManufacturerAmbeed
Product numberA113750
Product descriptionMS436 98+%
Packaging10mg
Price$88
Updated2021-12-16
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ManufacturerAmbeed
Product numberA113750
Product descriptionMS436 98+%
Packaging50mg
Price$148
Updated2021-12-16
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ManufacturerAmbeed
Product numberA113750
Product descriptionMS436 98+%
Packaging100mg
Price$236
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113750
Product descriptionMS436 98+%
Packaging1g
Price$1181
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB1012
Product descriptionMS436
Packaging25mg
Price$243
Updated2021-12-16
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ManufacturerBroadPharm
Product numberBP-23376
Product descriptionMS-436 98%
Packaging100mg
Price$490
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-1729
Product descriptionMS436 99.13%
Packaging5mg
Price$90
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-1729
Product descriptionMS436 99.13%
Packaging10mg
Price$125
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-1729
Product descriptionMS436 99.13%
Packaging50mg
Price$450
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-1729
Product descriptionMS436 99.13%
Packaging100mg
Price$650
Updated2021-12-16
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ManufacturerCrysdot
Product numberCD31003636
Product descriptionMS436 98+%
Packaging50mg
Price$509
Updated2021-12-16
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ManufacturerCrysdot
Product numberCD31003636
Product descriptionMS436 98+%
Packaging100mg
Price$868
Updated2021-12-16
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ManufacturerDC Chemicals
Product numberDC7620
Product descriptionMS436 >98%
Packaging250mg
Price$600
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	Y1865	MS436	10mg	$218.75	2021-12-16	Buy
AK Scientific	Y1865	MS436	100mg	$927.5	2021-12-16	Buy
Ambeed	A113750	MS436 98+%	5mg	$67	2021-12-16	Buy
Ambeed	A113750	MS436 98+%	10mg	$88	2021-12-16	Buy
Ambeed	A113750	MS436 98+%	50mg	$148	2021-12-16	Buy
Ambeed	A113750	MS436 98+%	100mg	$236	2021-12-16	Buy
Ambeed	A113750	MS436 98+%	1g	$1181	2021-12-16	Buy
ApexBio Technology	B1012	MS436	25mg	$243	2021-12-16	Buy
BroadPharm	BP-23376	MS-436 98%	100mg	$490	2021-12-16	Buy
ChemScene	CS-1729	MS436 99.13%	5mg	$90	2021-12-16	Buy
ChemScene	CS-1729	MS436 99.13%	10mg	$125	2021-12-16	Buy
ChemScene	CS-1729	MS436 99.13%	50mg	$450	2021-12-16	Buy
ChemScene	CS-1729	MS436 99.13%	100mg	$650	2021-12-16	Buy
Crysdot	CD31003636	MS436 98+%	50mg	$509	2021-12-16	Buy
Crysdot	CD31003636	MS436 98+%	100mg	$868	2021-12-16	Buy
DC Chemicals	DC7620	MS436 >98%	250mg	$600	2021-12-16	Buy

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Properties

Boiling point :673.7±65.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥19.15 mg/mL in DMSO
form :solid
pka :9.25±0.36(Predicted)
color :Pink to red

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

MS436, through a set of water-mediated interactions, exhibits low nanomolar affinity (estimated Ki of 30-50 nM) with preference for the first bromodomain over the second. MS436 effectively blocks BRD4 transcriptional activity in lipopolysaccharide-induced production of both nitric oxide and IL-6 in mouse macrophages (IC50 values are 3.8 and 4.9 ?M, respectively). MS436 represents a new class of bromodomain inhibitors and will facilitate further investigation of the biological functions of the two bromodomains of BRD4 in gene expression.

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Suppliers and manufacturers

career henan chemical co

$1.00 /1KG
(E)-4-((2-AMINO-4-HYDROXY-5-METHYLPHENYL)DIAZENYL)-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE CAS:1395084-25-9

TargetMol Chemicals Inc.

$59.00 /5mg
MS436 CAS:1395084-25-9

ATK CHEMICAL COMPANY LIMITED

Hubei Jusheng Technology Co.,Ltd.

BOC Sciences

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Dideu Industries Group Limited

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

ShenZhen Trendseen Biological Technology Co.,Ltd.

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MS436

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Description

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