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ChemicalBook >> CAS DataBase List >> Mubritinib

Mubritinib

$24 - $2023
Product name: Mubritinib
CAS: 366017-09-6
MF: C25H23F3N4O2
MW: 468.47
EINECS:
MDL Number:MFCD09954135
Synonyms:MUBRITINIB;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;TAK 165;Mubritinib(TAK 165);CS-522;TAK165;TAK-165;(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165)

Price65 Properties Safety Information Description

65 prices

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Brand

aablocks
Adipogen Life Sciences
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chem-Impex
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
TCI Chemical
Tocris
TRC
Usbiological

Package

1MG
10
1unit
5mg
10mg
10mM*1mLinDMSO
25mg
50
20mg
50mg
200mg
250mg
1g
100mg
1000mg
10mM(1mLinDMSO)

Manufactureraablocks
Product numberAA0078QG
Product description1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98
Packaging50mg
Price$167
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0078QG
Product description1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98
Packaging100mg
Price$299
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0078QG
Product description1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98%
Packaging10mg
Price$38
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0078QG
Product description1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98%
Packaging5mg
Price$24
Updated2026-05-28
Buy

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3755-M005
Product descriptionMubritinib ≥95%
Packaging5mg
Price$30
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3755-M025
Product descriptionMubritinib ≥95%
Packaging25mg
Price$120
Updated2021-12-16
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ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3755-M025
Product descriptionMubritinib ≥95%
Packaging25mg
Price$120
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product numberSYN1112
Product descriptionMubritinib
Packaging5mg
Price$85
Updated2021-12-16
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ManufacturerAK Scientific
Product numberSYN1112
Product descriptionMubritinib
Packaging10mg
Price$90
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000892
Product descriptionMUBRITINIB 95.00%
Packaging1MG
Price$166.95
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000892
Product descriptionMUBRITINIB 95.00%
Packaging50MG
Price$1352.22
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000892
Product descriptionMUBRITINIB 95.00%
Packaging10MG
Price$726.44
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1543
Product descriptionMubritinib (TAK 165)
Packaging100mg
Price$412
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB1543
Product descriptionMubritinib(TAK165)
Packaging200mg
Price$610
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1543
Product descriptionMubritinib (TAK 165)
Packaging50mg
Price$219
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB1543
Product descriptionMubritinib(TAK165)
Packaging1unit
Price$28
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0078QG	1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98	50mg	$167	2026-05-28	Buy
aablocks	AA0078QG	1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98	100mg	$299	2026-05-28	Buy
aablocks	AA0078QG	1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98%	10mg	$38	2026-05-28	Buy
aablocks	AA0078QG	1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole 98%	5mg	$24	2026-05-28	Buy
Adipogen Life Sciences	AG-CR1-3755-M005	Mubritinib ≥95%	5mg	$30	2026-05-06	Buy
Adipogen Life Sciences	AG-CR1-3755-M025	Mubritinib ≥95%	25mg	$120	2021-12-16	Buy
Adipogen Life Sciences	AG-CR1-3755-M025	Mubritinib ≥95%	25mg	$120	2026-05-06	Buy
AK Scientific	SYN1112	Mubritinib	5mg	$85	2021-12-16	Buy
AK Scientific	SYN1112	Mubritinib	10mg	$90	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000892	MUBRITINIB 95.00%	1MG	$166.95	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000892	MUBRITINIB 95.00%	50MG	$1352.22	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000892	MUBRITINIB 95.00%	10MG	$726.44	2021-12-16	Buy
ApexBio Technology	B1543	Mubritinib (TAK 165)	100mg	$412	2026-05-06	Buy
ApexBio Technology	B1543	Mubritinib(TAK165)	200mg	$610	2021-12-16	Buy
ApexBio Technology	B1543	Mubritinib (TAK 165)	50mg	$219	2026-05-06	Buy
ApexBio Technology	B1543	Mubritinib(TAK165)	1unit	$28	2021-12-16	Buy

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Properties

Melting point :158.0 to 162.0 °C
Boiling point :620.9±65.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO : 50 mg/mL (106.73 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder to crystal
pka :1.45±0.10(Predicted)
color :White to Gray to Brown
InChI :InChI=1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+
InChIKey :ZTFBIUXIQYRUNT-MDWZMJQESA-N
SMILES :N1(CCCCC2=CC=C(OCC3=COC(/C=C/C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2)C=CN=N1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H320	Causes eye irritation	Serious eye damage/eye irritation	Category 2B	Warning	P264, P305+P351+P338,P337+P313
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mubritinib is a selective inhibitor of the human epidermal growth factor receptor 2 (HER2), inhibiting HER2 phosphorylation with an IC50 value of 6 nM. It is without effect on EGFR, FGFR, PDGFR, JAK1, Src, and Blk (IC50 > 25 μM). Mubritinib inhibits the proliferation of breast, bladder, kidney, and prostate cancer cells in vitro and in vivo.

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Suppliers and manufacturers

career henan chemical co

$3.00
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Dideu Industries Group Limited

$1.10
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Mubritinib

Properties

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Description

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