NSC 42834
|
- $36 - $3624
- Product name: NSC 42834
- CAS: 195371-52-9
- MF: C23H24N2O
- MW: 344.45
- EINECS:
- MDL Number:MFCD00023550
- Synonyms:JAK2 Inhibitor V, Z3;NSC 42834;1-Butanone, 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-;2-METHYL-1-PHENYL-4-(PYRIDIN-2-YL)-2-(2-(PYRIDIN-2-YL)ETHYL)BUTAN-1-ONE;2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;NSC 42834 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-;Z3;NSC 42834;1-BUTANONE; 2-METHYL-1-PHENYL-4-(2-PYRIDINYL)-2-[2-(2-PYRIDINYL)ETHYL]-
23 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 10mM*1mLinDMSO
- 50mg
- 100mg
- 250MG
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA00ABIA
- Product descriptionNSC 42834 ≥95%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABIA
- Product descriptionNSC 42834
- Packaging2mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABIA
- Product descriptionNSC 42834
- Packaging5mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABIA
- Product descriptionNSC 42834
- Packaging10mg
- Price$82
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33937
- Product descriptionNSC 42834 98%
- Packaging250MG
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33937
- Product descriptionNSC 42834 98%
- Packaging1G
- Price$520
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3183AH
- Product description2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
- Packaging100mg
- Price$1237
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3183AH
- Product description2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
- Packaging500mg
- Price$3624
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3514
- Product descriptionJAK2 Inhibitor V, Z3
- Packaging5mg
- Price$78
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging5mg
- Price$86
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging25mg
- Price$294
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging10mg
- Price$135
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC 42834 96.85%
- Packaging50mg
- Price$417
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC 42834 96.85%
- Packaging100mg
- Price$775
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC 42834 96.85%
- Packaging10mg
- Price$107
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABIA | NSC 42834 ≥95% | 1mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00ABIA | NSC 42834 | 2mg | $47 | 2026-05-28 | Buy |
| aablocks | AA00ABIA | NSC 42834 | 5mg | $62 | 2026-05-28 | Buy |
| aablocks | AA00ABIA | NSC 42834 | 10mg | $82 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33937 | NSC 42834 98% | 250MG | $200 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33937 | NSC 42834 98% | 1G | $520 | 2026-05-27 | Buy |
| AK Scientific | 3183AH | 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one | 100mg | $1237 | 2021-12-16 | Buy |
| AK Scientific | 3183AH | 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one | 500mg | $3624 | 2021-12-16 | Buy |
| ApexBio Technology | A3514 | JAK2 Inhibitor V, Z3 | 5mg | $78 | 2026-05-06 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 5mg | $86 | 2026-04-30 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 25mg | $294 | 2026-04-30 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 10mg | $135 | 2026-04-30 | Buy |
| ChemScene | CS-1006 | NSC 42834 96.85% | 50mg | $417 | 2026-06-04 | Buy |
| ChemScene | CS-1006 | NSC 42834 96.85% | 100mg | $775 | 2026-06-04 | Buy |
| ChemScene | CS-1006 | NSC 42834 96.85% | 10mg | $107 | 2026-06-04 | Buy |
Properties
Boiling point :520.4±50.0 °C(Predicted)
Density :1.106±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :Powder
pka :5.90±0.12(Predicted)
color :Colorless to light yellow
InChI :1S/C23H24N2O/c1-23(15-13-20-11-5-7-17-24-20,16-14-21-12-6-8-18-25-21)22(26)19-9-3-2-4-10-19/h2-12,17-18H,13-16H2,1H3
InChIKey :SETYDCSRABYHSW-UHFFFAOYSA-N
Density :1.106±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :Powder
pka :5.90±0.12(Predicted)
color :Colorless to light yellow
InChI :1S/C23H24N2O/c1-23(15-13-20-11-5-7-17-24-20,16-14-21-12-6-8-18-25-21)22(26)19-9-3-2-4-10-19/h2-12,17-18H,13-16H2,1H3
InChIKey :SETYDCSRABYHSW-UHFFFAOYSA-N
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | |||||||
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| Precautionary statements: |
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Description
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 in which a switch from valine to phenylalanine occurs at the 617 position (V617F). JAK2 Inhibitor V is an inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 μM. It has no effect on Tyk2 or c-Src kinase function. JAK2 Inhibitor V blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F.More related product prices
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Suppliers and manufacturers
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