Oprozomib
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- $45 - $3728.1
- Product name: Oprozomib
- CAS: 935888-69-0
- MF: C25H32N4O7S
- MW: 532.61
- EINECS:
- MDL Number:MFCD25976563
- Synonyms:ONX-0912;OprozoMib;OprozoMib (ONX-0912);Ortho-Methyl-N-[(2-Methyl-5-Thiazolyl)Carbonyl]- L-Seryl-Ortho-Methyl-N-[(1s)-2-[(2r)-2-Methyl-2- Oxiranyl]-L-Serinamide;CS-696;LY335979 ONX-0912;N-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide;O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide
35 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3672-M001
- Product descriptionOprozomib[ONX0912] ≥98%(HPLC)
- Packaging1mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3672-M001
- Product descriptionOprozomib [ONX 0912] ≥98%(HPLC)
- Packaging1mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3672-M005
- Product descriptionOprozomib [ONX 0912] ≥98%(HPLC)
- Packaging5mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN5719
- Product descriptionOprozomib
- Packaging10mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib (ONX-0912)
- Packaging25mg
- Price$330
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib (ONX-0912)
- Packaging10mg
- Price$176
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib (ONX-0912)
- Packaging5mg
- Price$116
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib (ONX-0912)
- Packaging10mM(in1mLDMSO)
- Price$132
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib(ONX-0912)
- Packaging100mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1934
- Product descriptionOprozomib (ONX-0912)
- Packaging100mg
- Price$660
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberCFN60429
- Product descriptionOprozomib(ONX0912) ≥98%
- Packaging10mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146097
- Product descriptionOprozomib (ONX-0912) >98%
- Packaging100mg
- Price$950.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146097
- Product descriptionOprozomib (ONX-0912) >98%
- Packaging250mg
- Price$1876.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146097
- Product descriptionOprozomib (ONX-0912) >98%
- Packaging1g
- Price$3728.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO65113
- Product descriptionOprozomib
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO65113
- Product descriptionOprozomib
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3672-M001 | Oprozomib[ONX0912] ≥98%(HPLC) | 1mg | $45 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3672-M001 | Oprozomib [ONX 0912] ≥98%(HPLC) | 1mg | $60 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3672-M005 | Oprozomib [ONX 0912] ≥98%(HPLC) | 5mg | $160 | 2026-05-06 | Buy |
| AK Scientific | SYN5719 | Oprozomib | 10mg | $217 | 2021-12-16 | Buy |
| ApexBio Technology | A1934 | Oprozomib (ONX-0912) | 25mg | $330 | 2026-05-06 | Buy |
| ApexBio Technology | A1934 | Oprozomib (ONX-0912) | 10mg | $176 | 2026-05-06 | Buy |
| ApexBio Technology | A1934 | Oprozomib (ONX-0912) | 5mg | $116 | 2026-05-06 | Buy |
| ApexBio Technology | A1934 | Oprozomib (ONX-0912) | 10mM(in1mLDMSO) | $132 | 2026-05-06 | Buy |
| ApexBio Technology | A1934 | Oprozomib(ONX-0912) | 100mg | $600 | 2021-12-16 | Buy |
| ApexBio Technology | A1934 | Oprozomib (ONX-0912) | 100mg | $660 | 2026-05-06 | Buy |
| Arctom | CFN60429 | Oprozomib(ONX0912) ≥98% | 10mg | $378 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146097 | Oprozomib (ONX-0912) >98% | 100mg | $950.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146097 | Oprozomib (ONX-0912) >98% | 250mg | $1876.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146097 | Oprozomib (ONX-0912) >98% | 1g | $3728.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO65113 | Oprozomib | 10mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO65113 | Oprozomib | 50mg | $612.5 | 2021-12-16 | Buy |
Properties
Melting point :147-150°C (dec.)
Boiling point :849.9±65.0 °C(Predicted)
Density :1.290±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.29±0.46(Predicted)
form :Solid
color :White to Off-White
Boiling point :849.9±65.0 °C(Predicted)
Density :1.290±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.29±0.46(Predicted)
form :Solid
color :White to Off-White
Safety Information
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Description
ONX 0912 is an orally bioavailable proteasome inhibitor. It potently targets the chymotrypsin-like activity of the 20S proteasome subunits β5 and LMP7 (IC50s = 36 and 82 nM, respectively). ONX 0912 inhibits the growth of multiple myeloma cells at nanomolar concentrations while not decreasing the viability of normal peripheral blood mononuclear cells at 1 μM. It blocks the growth of xenografted human multiple myeloma cells in mice when given orally. ONX 0912 has potential applications in certain types of cancer as well as other diseases that require proteasome activity.Related product price
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