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ChemicalBook >> CAS DataBase List >> PLX8394

PLX8394

$28 - $4766.8
Product name: PLX8394
CAS: 1393466-87-9
MF: C25H21F3N6O3S
MW: 542.53
EINECS:
MDL Number:MFCD29472263
Synonyms:PLX8394;PLX8394;PLX-8394;PLX 8394;1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-;(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide;PLX8394,PLX-8394;(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide;PLX8394, 10 mM in DMSO

Price47 Properties Safety Information Description

47 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
Arctom
Biorbyt Ltd
Biosynth
ChemScene
Crysdot
DC Chemicals

Package

10mM*1mLinDMSO(Solution)
1mg
2mg
10mM*1mLinDMSO(Solid+Solvent)
5mg
10mg
25mg
50mg
100mg
250mg
1G

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging1mg
Price$32
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging2mg
Price$38
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging5mg
Price$46
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging10mg
Price$68
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging25mg
Price$113
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging50mg
Price$189
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging100mg
Price$339
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CGY
Product description(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%
Packaging250mg
Price$847
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberS88553
Product descriptionPLX8394 98%
Packaging1G
Price$2450
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberS88553
Product descriptionPLX8394 98%
Packaging100MG
Price$640
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberS88553
Product descriptionPLX8394 98%
Packaging25MG
Price$245
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberS88553
Product descriptionPLX8394 98%
Packaging5MG
Price$90
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number3017EB
Product description(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging10mg
Price$164
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3017EB
Product description(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging50mg
Price$451
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA840010
Product descriptionPLX8394 98+%
Packaging100mg
Price$445
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA840010
Product descriptionPLX8394 98+%
Packaging50mg
Price$223
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	1mg	$32	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	2mg	$38	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	5mg	$46	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	10mg	$68	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	25mg	$113	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	50mg	$189	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	100mg	$339	2026-05-28	Buy
aablocks	AA009CGY	(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide 98%	250mg	$847	2026-05-28	Buy
ACHEMBLOCK	S88553	PLX8394 98%	1G	$2450	2026-05-27	Buy
ACHEMBLOCK	S88553	PLX8394 98%	100MG	$640	2026-05-27	Buy
ACHEMBLOCK	S88553	PLX8394 98%	25MG	$245	2026-05-27	Buy
ACHEMBLOCK	S88553	PLX8394 98%	5MG	$90	2026-05-27	Buy
AK Scientific	3017EB	(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide	10mg	$164	2021-12-16	Buy
AK Scientific	3017EB	(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide	50mg	$451	2021-12-16	Buy
Ambeed	A840010	PLX8394 98+%	100mg	$445	2021-12-16	Buy
Ambeed	A840010	PLX8394 98+%	50mg	$223	2021-12-16	Buy

Next Last

Properties

Density :1.60±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 39 mg/mL (71.89 mM);Water : < 0.1 mg/mL (insoluble)
form :Solid
pka :6.33±0.40(Predicted)
color :White to light yellow
InChIKey :YYACLQUDUDXAPA-MRXNPFEDSA-N
SMILES :N1(S(NC2=CC=C(F)C(C(C3C4=CC(C5=CN=C(C6CC6)N=C5)=CN=C4NC=3)=O)=C2F)(=O)=O)CC[C@@H](F)C1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Combination therapies comprising KRAS G12C inhibitors and Raf kinase inhibitors for treating KRAS G12C cancers.BRAF inhibitor.

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PLX8394

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Description

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