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ChemicalBook >> CAS DataBase List >> PLX-4720

PLX-4720

PLX-4720 price.
  • $9 - $1133.9
  • Product name: PLX-4720
  • CAS: 918505-84-7
  • MF: C17H14ClF2N3O3S
  • MW: 413.83
  • EINECS:
  • MDL Number:MFCD14635203
  • Synonyms:1-PropanesulfonaMide, N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-;N-[3-[(5-Chloro-1H-pyrrol...;N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide PLX 4720;PLX-4720;PLX 4720;PLX4720;RAF KINASE INHIBITOR V;CS-1917;PLX-4720;PLX 4720;PLX4720;PLX 4720 N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide;PLX4720, >=98%
Price61 Properties Safety Information Description
61 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 2mg
  • 10mM*1mLinDMSO(Solution)
  • 250.00mg
  • 1.00g
  • EvaluationSample
  • 10mM*1mLinDMSO
  • 5.00g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging1mg
  • Price$9
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging5mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging10mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging25mg
  • Price$20
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging50mg
  • Price$24
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging100mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging250mg
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+%
  • Packaging1g
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GRRZ
  • Product descriptionn-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 98%
  • Packaging5g
  • Price$490
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-5861
  • Product descriptionN-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97%
  • Packaging1G
  • Price$215
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-5861
  • Product descriptionN-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97%
  • Packaging5G
  • Price$645
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-5861
  • Product descriptionN-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97%
  • Packaging100MG
  • Price$45
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3577-M005
  • Product descriptionPLX4720 ≥99%(HPLC)
  • Packaging5mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3577-M025
  • Product descriptionPLX4720 ≥99%(HPLC)
  • Packaging25mg
  • Price$150
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7406
  • Product descriptionPLX-4720
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3016
  • Product descriptionPLX-4720
  • Packaging10mM(in1mLDMSO)
  • Price$61
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 1mg $9 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 5mg $13 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 10mg $16 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 25mg $20 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 50mg $24 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 100mg $31 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 250mg $40 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 99+% 1g $99 2026-05-28 Buy
aablocks AA00GRRZ n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 98% 5g $490 2026-05-28 Buy
ACHEMBLOCK G-5861 N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97% 1G $215 2026-05-27 Buy
ACHEMBLOCK G-5861 N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97% 5G $645 2026-05-27 Buy
ACHEMBLOCK G-5861 N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide 97% 100MG $45 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3577-M005 PLX4720 ≥99%(HPLC) 5mg $50 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3577-M025 PLX4720 ≥99%(HPLC) 25mg $150 2026-05-06 Buy
AK Scientific X7406 PLX-4720 5mg $60 2021-12-16 Buy
ApexBio Technology A3016 PLX-4720 10mM(in1mLDMSO) $61 2026-05-06 Buy
Next Last

Properties

Melting point :230-233oC
Density :1.55
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Orange-yellow solid
pka :6.20±0.10(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. Mutations in the kinase B-Raf are involved in a wide range of cancers. In particular, the mutation B-RafV600E occurs in melanomas and thyroid cancer but is poorly targeted by many inhibitors of wild type B-Raf. PLX4720 is an orally-available, highly selective inhibitor of B-RafV600E (IC50 = 13 nM). It is less effective against wild type B-Raf (IC50 = 160 nM) as well as several other kinases. PLX4720 induces cell cycle arrest and apoptosis in cells and xenografts expressing the mutant of B-Raf.

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Suppliers and manufacturers

career henan chemical co
N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
$1.00
N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide CAS:918505-84-7
TargetMol Chemicals Inc.
PLX-4720
$48.00
PLX-4720 CAS:918505-84-7
Capot Chemical Co.,Ltd.
Shenzhen Nexconn Pharmatechs Ltd
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Finetech Industry Limited
Zhejiang J&C Biological Technology Co.,Limited
Wuhu Nuowei chemistry Co., Ltd.
HANGZHOU LEAP CHEM CO., LTD.