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ChemicalBook >> CAS DataBase List >> PVM/MA

PVM/MA

PVM/MA price.
  • $90 - $1800
  • Product name: PVM/MA
  • CAS: 1644545-52-7
  • MF: C14H13ClF6N6
  • MW: 414.74
  • EINECS:
  • MDL Number:MFCD31630835
  • Synonyms:PF06291874;Vorasidenib;E7386;E-7386;s-22611;FM381 FM-381;6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine;PVM/MA
12 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1934EF
  • Product descriptionVorasidenib
  • Packaging5mg
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28462
  • Product descriptionVorasidenib
  • Packaging1mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28462
  • Product descriptionVorasidenib
  • Packaging5mg
  • Price$433
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28462
  • Product descriptionVorasidenib
  • Packaging10mg
  • Price$757
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8033
  • Product descriptionVorasidenib 99.87%
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8033
  • Product descriptionVorasidenib 99.87%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8033
  • Product descriptionVorasidenib 99.87%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8033
  • Product descriptionVorasidenib 99.87%
  • Packaging50mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8033
  • Product descriptionVorasidenib 99.87%
  • Packaging100mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10439
  • Product descriptionVorasidenib(AG881) >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10439
  • Product descriptionVorasidenib(AG881) >98%
  • Packaging250mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10439
  • Product descriptionVorasidenib(AG881) >98%
  • Packaging1g
  • Price$1800
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1934EF Vorasidenib 5mg $580 2021-12-16 Buy
Cayman Chemical 28462 Vorasidenib 1mg $110 2024-03-01 Buy
Cayman Chemical 28462 Vorasidenib 5mg $433 2024-03-01 Buy
Cayman Chemical 28462 Vorasidenib 10mg $757 2024-03-01 Buy
ChemScene CS-8033 Vorasidenib 99.87% 2mg $90 2021-12-16 Buy
ChemScene CS-8033 Vorasidenib 99.87% 5mg $150 2021-12-16 Buy
ChemScene CS-8033 Vorasidenib 99.87% 10mg $250 2021-12-16 Buy
ChemScene CS-8033 Vorasidenib 99.87% 50mg $750 2021-12-16 Buy
ChemScene CS-8033 Vorasidenib 99.87% 100mg $1100 2021-12-16 Buy
DC Chemicals DC10439 Vorasidenib(AG881) >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC10439 Vorasidenib(AG881) >98% 250mg $900 2021-12-16 Buy
DC Chemicals DC10439 Vorasidenib(AG881) >98% 1g $1800 2021-12-16 Buy

Properties

Boiling point :467.5±55.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form :A crystalline solid
pka :1.49±0.41(Predicted)
color :Light yellow to light brown
InChI :InChI=1S/C14H13ClF6N6/c1-6(13(16,17)18)22-11-25-10(8-4-3-5-9(15)24-8)26-12(27-11)23-7(2)14(19,20)21/h3-7H,1-2H3,(H2,22,23,25,26,27)/t6-,7-/m1/s1
InChIKey :QCZAWDGAVJMPTA-RNFRBKRXSA-N
SMILES :N1=C(C2=NC(Cl)=CC=C2)N=C(N[C@H](C)C(F)(F)F)N=C1N[C@H](C)C(F)(F)F

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.

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