Ritlecitinib
|
- $47 - $2500
- Product name: Ritlecitinib
- CAS: 1792180-81-4
- MF: C15H19N5O
- MW: 285.34
- EINECS:210-077-2
- MDL Number:MFCD31697544
- Synonyms:1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one;1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2;PF-06651600;PF 06651600;PF06651600;1-[(2S,5R)-2-methyl-5(7H-pyrrolo[2,3-d]pyrimidine-4-ylamino)-1-piperidinly]-2-propen-1-one malonate,PF06651600;Ritlecitinib;2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-;1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one;Ritlecitinib (PF-06651600)
30 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Alichem
- American Custom Chemicals Corporation
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Usbiological
Package
- 2mg
- 10mM*1mLinDMSO
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 500mg
- 1g
- Manufactureraablocks
- Product numberAA0026RT
- Product descriptionRitlecitinib 95
- Packaging2mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0026RT
- Product descriptionRitlecitinib 95%
- Packaging100mg
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0026RT
- Product descriptionRitlecitinib 95%
- Packaging1g
- Price$467
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193539
- Product description1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00%
- Packaging250MG
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193539
- Product description1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00%
- Packaging1G
- Price$325
- Updated2026-05-27
- Buy
- ManufacturerAlichem
- Product number1792180814
- Product description1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
- Packaging100mg
- Price$829.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002534
- Product descriptionPF-06651600 95.00%
- Packaging5MG
- Price$457.78
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBP168506
- Product descriptionPF 06651600
- Packaging25mg
- Price$357
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBP168506
- Product descriptionPF 06651600
- Packaging10mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBP168506
- Product descriptionPF 06651600
- Packaging2mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBP168506
- Product descriptionPF 06651600
- Packaging5mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBP168506
- Product descriptionPF 06651600
- Packaging50mg
- Price$571
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number21054
- Product descriptionPF-06651600 ≥95%
- Packaging250mg
- Price$1241
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21054
- Product descriptionPF-06651600 ≥95%
- Packaging100mg
- Price$767
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21054
- Product descriptionPF-06651600 ≥95%
- Packaging50mg
- Price$429
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21054
- Product descriptionPF-06651600 ≥95%
- Packaging10mg
- Price$91
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0026RT | Ritlecitinib 95 | 2mg | $47 | 2026-05-28 | Buy |
| aablocks | AA0026RT | Ritlecitinib 95% | 100mg | $50 | 2026-05-28 | Buy |
| aablocks | AA0026RT | Ritlecitinib 95% | 1g | $467 | 2026-05-28 | Buy |
| ACHEMBLOCK | X193539 | 1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00% | 250MG | $120 | 2026-05-27 | Buy |
| ACHEMBLOCK | X193539 | 1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00% | 1G | $325 | 2026-05-27 | Buy |
| Alichem | 1792180814 | 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one | 100mg | $829.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002534 | PF-06651600 95.00% | 5MG | $457.78 | 2021-12-16 | Buy |
| Biosynth | BP168506 | PF 06651600 | 25mg | $357 | 2026-06-04 | Buy |
| Biosynth | BP168506 | PF 06651600 | 10mg | $250 | 2026-06-04 | Buy |
| Biosynth | BP168506 | PF 06651600 | 2mg | $250 | 2026-06-04 | Buy |
| Biosynth | BP168506 | PF 06651600 | 5mg | $250 | 2026-06-04 | Buy |
| Biosynth | BP168506 | PF 06651600 | 50mg | $571 | 2026-06-04 | Buy |
| Cayman Chemical | 21054 | PF-06651600 ≥95% | 250mg | $1241 | 2026-04-30 | Buy |
| Cayman Chemical | 21054 | PF-06651600 ≥95% | 100mg | $767 | 2026-04-30 | Buy |
| Cayman Chemical | 21054 | PF-06651600 ≥95% | 50mg | $429 | 2026-04-30 | Buy |
| Cayman Chemical | 21054 | PF-06651600 ≥95% | 10mg | $91 | 2026-04-30 | Buy |
Properties
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO:100.0(Max Conc. mg/mL);350.4(Max Conc. mM)
H2O:5.0(Max Conc. mg/mL);17.5(Max Conc. mM) form :powder
pka :13.03±0.50(Predicted)
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES :C(N1C[C@H](NC2N=CN=C3NC=CC3=2)CC[C@@H]1C)(=O)C=C
storage temp. :room temp
solubility :DMSO:100.0(Max Conc. mg/mL);350.4(Max Conc. mM)
H2O:5.0(Max Conc. mg/mL);17.5(Max Conc. mM) form :powder
pka :13.03±0.50(Predicted)
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES :C(N1C[C@H](NC2N=CN=C3NC=CC3=2)CC[C@@H]1C)(=O)C=C
Safety Information
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Description
Ritlecitinib, a dual JAK3/TEC inhibitor, was granted FDA breakthrough status for treating alopecia areata (autoimmune-induced hair loss) in September 2018. Promising phase 3 trial results in alopecia areata were reported by Pfizer in August 2021, placing it in competition with Lilly/Incyte’s Olumiant. It is also used in clinical studies to treat vitiligo, rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. Ritlecitinib achieved high JAK3 selectivity via covalent interaction with a unique cysteine residue (Cys909) in the catalytic domain.More related product prices
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Suppliers and manufacturers
Jinan Jianfeng Chemical Co., Ltd
Ritlecitinib
CAS:1792180-81-4
Dingwang Technology (Wuhan) Co., Ltd.
Suzhou ARTK Medchem Co., Ltd.
BOC Sciences
CONIER CHEM AND PHARMA LIMITED
Suzhou Ryan Pharmachem Technology Co.,Ltd.
Shanghai UCHEM Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
Ritlecitinib
CAS:1792180-81-4
